BIOMED Biomedical Research Institute, Hasselt University, Diepenbeek, Belgium.
Mult Scler. 2013 Sep;19(10):1341-8. doi: 10.1177/1352458513475832. Epub 2013 Feb 13.
The real-life relevance of frequently applied clinical arm tests is not well known in multiple sclerosis (MS).
This study aimed to determine the relation between real-life arm performance and clinical tests in MS.
Thirty wheelchair-bound MS patients and 30 healthy controls were included. Actual and perceived real-life arm performance was measured by using accelerometry and a self-reported measure (Motor Activity Log). Clinical tests on 'body functions & structures' (JAMAR handgrip strength, Motricity Index (MI), Fugl Meyer (FM)) and 'activity' level (Nine Hole Peg Test (NHPT), Action Research Arm test) of the International Classification of Functioning were conducted. Statistical analyses were performed separately for current dominant and non-dominant arm.
For all outcome measures, MS patients scored with both arms significantly lower than the control group. Higher correlations between actual arm performance and clinical tests were found for the non-dominant arm (0.63-0.80). The FM (55%) was a good predictor of actual arm performance, while the MI (46%) and NHPT (55%) were good predictors of perceived arm performance.
Real-life arm performance is decreased in wheelchair-bound MS patients and can be best predicted by measures on 'body functions & structures' level and fine motor control. Hand dominance influenced the magnitude of relationships.
在多发性硬化症（MS）中，经常应用的临床手臂测试的实际相关性并不为人所知。
本研究旨在确定 MS 患者真实生活中的手臂表现与临床测试之间的关系。
纳入 30 名坐轮椅的 MS 患者和 30 名健康对照者。使用加速度计和自我报告的测量工具（运动活动日志）来测量实际和感知的真实生活中的手臂表现。进行了国际功能分类关于“身体功能和结构”（JAMAR 手握力、运动能力指数（MI）、Fugl Meyer（FM））和“活动”水平（九孔钉测试（NHPT）、行动研究手臂测试）的临床测试。分别对当前优势和非优势手臂进行统计分析。
对于所有的结果测量，MS 患者的两支手臂的得分都明显低于对照组。非优势手臂的实际手臂表现与临床测试之间的相关性更高（0.63-0.80）。FM（55%）是实际手臂表现的良好预测指标，而 MI（46%）和 NHPT（55%）是感知手臂表现的良好预测指标。
坐轮椅的 MS 患者的真实生活中的手臂表现下降，并且可以通过“身体功能和结构”水平和精细运动控制的测量来最好地预测。手的优势影响了关系的大小。
