Nigro Olivia D, Culley Alexander I, Steward Grieg F
University of Hawaii Department of Oceanography Center for Microbial Oceanography: Research and Education Honolulu, HI.
Stand Genomic Sci. 2012 Jul 30;6(3):415-26. doi: 10.4056/sigs.2846206. Epub 2012 Jul 20.
Investigating the bacteriophages of vibrios has led to significant insights into the evolution and pathogenicity of their host strains. This report presents the first complete genome sequence of a bacteriophage that infects the deadly human pathogen Vibrio vulnificus. The phage was isolated from the surface waters of the Ala Wai Canal, which is part of an urban watershed in eastern Honolulu, Hawaii, USA. The phage particle is icosahedral, with a diameter of 35-40 nm, and a small non-contractile tail. The genome was sequenced in its entirety, rendering a 38 kb sequence located on a single, linear, circularly permuted chromosome. Here, we present the annotation and genomic features of the bacteriophage, VvAW1.
对弧菌噬菌体的研究为深入了解其宿主菌株的进化和致病性提供了重要见解。本报告展示了一种感染致命人类病原体创伤弧菌的噬菌体的首个完整基因组序列。该噬菌体是从阿拉韦运河的表层水体中分离出来的，阿拉韦运河是美国夏威夷州檀香山东部一个城市流域的一部分。噬菌体粒子呈二十面体，直径为35 - 40纳米，有一条短小的非收缩性尾部。对其基因组进行了全序列测定，得到了一个位于单一线性、环状排列染色体上的38千碱基序列。在此，我们展示了噬菌体VvAW1的注释和基因组特征。
