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ACT:阿耳忒弥斯比较工具。

ACT: the Artemis Comparison Tool.

作者信息

Carver Tim J, Rutherford Kim M, Berriman Matthew, Rajandream Marie-Adele, Barrell Barclay G, Parkhill Julian

机构信息

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.

出版信息

Bioinformatics. 2005 Aug 15;21(16):3422-3. doi: 10.1093/bioinformatics/bti553. Epub 2005 Jun 23.

Abstract

The Artemis Comparison Tool (ACT) allows an interactive visualisation of comparisons between complete genome sequences and associated annotations. The comparison data can be generated with several different programs; BLASTN, TBLASTX or Mummer comparisons between genomic DNA sequences, or orthologue tables generated by reciprocal FASTA comparison between protein sets. It is possible to identify regions of similarity, insertions and rearrangements at any level from the whole genome to base-pair differences. ACT uses Artemis components to display the sequences and so inherits powerful searching and analysis tools. ACT is part of the Artemis distribution and is similarly open source, written in Java and can run on any Java enabled platform, including UNIX, Macintosh and Windows.

摘要

阿尔忒弥斯比较工具(ACT)允许对完整基因组序列与相关注释之间的比较进行交互式可视化。比较数据可以通过几个不同的程序生成;基因组DNA序列之间的BLASTN、TBLASTX或Mummer比较,或蛋白质集之间通过相互FASTA比较生成的直系同源表。从全基因组到碱基对差异的任何水平,都可以识别相似性、插入和重排区域。ACT使用阿尔忒弥斯组件来显示序列,因此继承了强大的搜索和分析工具。ACT是阿尔忒弥斯发行版的一部分,同样是开源的,用Java编写,可以在任何支持Java的平台上运行,包括UNIX、Macintosh和Windows。

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