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在临床健康和感染曲霉菌属的猎鹰中,使用高分辨率琼脂糖凝胶进行血清蛋白电泳。

Serum protein electrophoresis by using high-resolution agarose gel in clinically healthy and Aspergillus species-infected falcons.

作者信息

Kummrow Maya, Silvanose Christudas, Di Somma Antonio, Bailey Thomas A, Vorbrüggen Susanne

机构信息

Zoo Hannover GmbH, Adenauerallee 3, 30175 Hannover, Germany.

出版信息

J Avian Med Surg. 2012 Dec;26(4):213-20. doi: 10.1647/2011-006R1.1.

Abstract

Serum protein electrophoresis has gained importance in avian medicine during the past decade. Interpretation of electrophoretic patterns should be based on species-specific reference intervals and the electrophoresis gel system. In this study, serum protein electrophoresis by using high-resolution agarose gels was performed on blood samples collected from 105 falcons, including peregrine falcons (Falco peregrinus), gyrfalcons (Falco rusticolus), saker falcons (Falco cherrug), red-naped shaheens (Falco pelegrinoides babylonicus), and hybrid falcons, that were submitted to the Dubai Falcon Hospital (Dubai, United Arab Emirates) between 2003 and 2006. Reference values were established in clinically healthy birds and compared with values from falcons infected with Aspergillus species (n = 32). Falcons with confirmed aspergillosis showed significantly lower prealbumin values, which is a novel finding. Prealbumin has been documented in many avian species, but further investigation is required to illuminate the diagnostic significance of this negative acute-phase protein.

摘要

在过去十年中,血清蛋白电泳在鸟类医学中变得愈发重要。电泳图谱的解读应基于物种特异性参考区间和电泳凝胶系统。在本研究中,对2003年至2006年间提交至迪拜猎鹰医院(阿拉伯联合酋长国迪拜)的105只猎鹰(包括矛隼、矛隼、猎隼、红颈隼和杂交猎鹰)采集的血液样本进行了使用高分辨率琼脂糖凝胶的血清蛋白电泳。在临床健康的鸟类中建立了参考值,并与感染曲霉菌种的猎鹰(n = 32)的值进行了比较。确诊为曲霉菌病的猎鹰显示前白蛋白值显著降低,这是一个新发现。前白蛋白已在许多鸟类物种中被记录,但需要进一步研究以阐明这种负急性期蛋白的诊断意义。

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