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亚裔美国大学生中的乙型肝炎病毒感染和免疫接种:感染、暴露和免疫率。

Hepatitis B virus infection and immunizations among Asian American college students: infection, exposure, and immunity rates.

机构信息

College of Nursing and Health Sciences, University of Massachusetts Boston, Boston, Massachusetts 02125-3393, USA.

出版信息

J Am Coll Health. 2013;61(2):67-74. doi: 10.1080/07448481.2012.753891.

DOI:10.1080/07448481.2012.753891
PMID:23409856
Abstract

OBJECTIVES

To evaluate the prevalence of hepatitis B virus (HBV) infection, exposure, and immunity among Asian American college students as a basis for evaluating HBV screening and vaccination policy.

PARTICIPANTS AND METHODS

Self-identified Asian American college students aged 18 years or older were examined. Serological tests of HBV surface antigens, antibodies to HBV core antigens (anti-HBc), and antibodies to HBV surface antigens (anti-HBs) were used to determine HBV infection and immunization prevalence.

RESULTS

Among US-born students (n = 66), none was infected with HBV, 68% (n = 45) had immunity from vaccination, and 1 student had evidence of past exposure to HBV. Among foreign-born students (n = 142), 4% (n = 5) had evidence of chronic HBV infection, 62% (n = 88) had immunity from vaccination, and 19% (n = 27) had results indicating past exposure to HBV. Asian American college students showed very little knowledge of HBV vaccination; 43% reported that they had received vaccination, whereas 50% did not know whether they had received it or not.

CONCLUSIONS

The prevalence of current and past HBV infection among foreign-born Asian American college students is significantly higher (p < .01), than US-born students. The lack of awareness of their HBV-infected status points out the importance of routine HBV screening of high-risk populations such as Asian students.

摘要

目的

评估亚裔美国大学生乙型肝炎病毒 (HBV) 感染、暴露和免疫的流行情况,为评估 HBV 筛查和疫苗接种政策提供依据。

参与者和方法

检查了自认为是亚裔美国的 18 岁或以上的大学生。使用 HBV 表面抗原、乙型肝炎核心抗原抗体 (抗-HBc) 和 HBV 表面抗原抗体 (抗-HBs) 的血清学检测来确定 HBV 感染和免疫的流行率。

结果

在美国出生的学生中(n = 66),没有 HBV 感染,68%(n = 45)有疫苗接种免疫,1 名学生有 HBV 既往暴露的证据。在外国出生的学生中(n = 142),4%(n = 5)有慢性 HBV 感染的证据,62%(n = 88)有疫苗接种免疫,19%(n = 27)有 HBV 既往暴露的结果。亚裔美国大学生对 HBV 疫苗接种知之甚少;43%的人报告接种过疫苗,而 50%的人不知道是否接种过。

结论

外国出生的亚裔美国大学生目前和既往 HBV 感染的流行率显著高于(p <.01)美国出生的学生。他们对 HBV 感染状态缺乏认识,这突显了对亚裔等高危人群进行常规 HBV 筛查的重要性。

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