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前瞻性随机对照试验研究手术固定连枷胸肋骨的疗效。

Prospective randomized controlled trial of operative rib fixation in traumatic flail chest.

机构信息

CJOB Cardiothoracic Surgery Department, The Alfred Hospital, Melbourne, Australia.

出版信息

J Am Coll Surg. 2013 May;216(5):924-32. doi: 10.1016/j.jamcollsurg.2012.12.024. Epub 2013 Feb 13.

Abstract

BACKGROUND

Traumatic flail chest injury is a potentially life threatening condition traditionally treated with invasive mechanical ventilation to splint the chest wall. Longer-term sequelae of pain, deformity, and physical restriction are well described. This study investigated the impact of operative fixation in these patients.

STUDY DESIGN

A prospective randomized study compared operative fixation of fractured ribs in the flail segment with current best practice mechanical ventilator management. In-hospital data, 3-month follow-up review, spirometry and CT, and 6-month quality of life (Short Form-36) questionnaire were collected.

RESULTS

Patients in the operative fixation group had significantly shorter ICU stay (hours) postrandomization (285 hours [range 191 to 319 hours] for the surgical group vs 359 hours [range 270 to 581 hours] for the conservative group; p = 0.03) and lesser requirement for noninvasive ventilation after extubation (3 hours [range 0 to 25 hours] in the surgical group vs 50 hours [range 17 to 102 hours] in the conservative group; p = 0.01). No differences in spirometry at 3 months or quality of life at 6 months were noted.

CONCLUSIONS

Operative fixation of fractured ribs reduces ventilation requirement and intensive care stay in a cohort of multitrauma patients with severe flail chest injury.

摘要

背景

创伤性连枷胸损伤是一种潜在危及生命的疾病,传统上采用有创机械通气来固定胸壁。疼痛、畸形和身体受限的长期后遗症已有详细描述。本研究调查了手术固定对这些患者的影响。

研究设计

前瞻性随机研究比较了手术固定连枷段骨折肋骨与当前最佳机械通气管理的效果。收集了住院期间的数据、3 个月随访评估、肺量测定和 CT 以及 6 个月的生活质量(SF-36 问卷)。

结果

手术固定组患者的 ICU 住院时间(小时)明显缩短(随机分组后 285 小时[范围 191 至 319 小时]与保守组 359 小时[范围 270 至 581 小时];p = 0.03),拔管后无创通气的需求也减少(手术组 3 小时[范围 0 至 25 小时]与保守组 50 小时[范围 17 至 102 小时];p = 0.01)。3 个月时的肺量测定或 6 个月时的生活质量无差异。

结论

在多创伤患者严重连枷胸损伤的队列中,手术固定肋骨骨折可减少通气需求和 ICU 住院时间。

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