Stürmer J, Schaer-Stoller F, Gloor B
Universitäts-Augenklinik Zürich.
Klin Monbl Augenheilkd. 1990 Mar;196(3):132-42. doi: 10.1055/s-2008-1046143.
Sixty-seven optic nerve heads of 40 patients with proven or suspected glaucoma were measured by planimetry and with the Rodenstock Optic Nerve Head Analyser (ONHA). The results were compared to visual field indices obtained with the Octopus program G-1. Good correlation of the results obtained by the two measurement procedures has been shown (Stürmer et al. 1989), between values for the disk area, the excavation area, and the cup/disk ratio. However, there is only weak correlation of values for the neuroretinal rim. The planimetrically measured neuroretinal rim area in the total population examined proved to be significantly correlated only with the visual field index for mean retinal sensitivity (MS; r2 = 0.106; P = 0.007) and short-term fluctuations (SF; r2 = 0.066; P = 0.036). After division of the population examined into different diagnostic groups, further statistically significant correlations between optic nerve head parameters and the various visual field indices were shown; here, the cup/disk ratio of both measurement procedures in two subgroups showed the best correlation with the visual field indices MS and mean defect (MD). Neither in the total population nor in any of the subgroups was a statistically significant correlation found between the volume of the excavation and one of the visual field indices. Comparing only the data for the temporal quadrant of the optic nerve head with the visual field did not improve the correlations. The best, i.e. highly significant, correlations were between optic nerve head parameters and the age of the patient. The correlation factors are much lower than other published data. A variety of factors could be responsible for these weak correlations: different optic nerve head configurations on the one hand, and localized or diffuse visual field defects on the other. In unselected cases it appears impossible to predict the visual field of a given optic nerve head. Both methods are suitable for follow-up, but not all anatomical configuration of the optic nerve head permit this.
采用平面测量法和罗登斯托克视神经乳头分析仪(ONHA)对40例已确诊或疑似青光眼患者的67个视神经乳头进行了测量。将测量结果与使用Octopus程序G-1获得的视野指数进行比较。结果表明,两种测量方法在视盘面积、杯状凹陷面积和杯盘比的值之间具有良好的相关性(施图默等人,1989年)。然而,神经视网膜边缘的值之间只有微弱的相关性。在所检查的总体人群中,平面测量的神经视网膜边缘面积仅与平均视网膜敏感度(MS;r2 = 0.106;P = 0.007)和短期波动(SF;r2 = 0.066;P = 0.036)的视野指数显著相关。将所检查的人群分为不同的诊断组后,视神经乳头参数与各种视野指数之间显示出进一步的统计学显著相关性;在此,两个亚组中两种测量方法的杯盘比与视野指数MS和平均缺损(MD)显示出最佳相关性。无论是在总体人群中还是在任何亚组中,均未发现杯状凹陷体积与任何视野指数之间存在统计学显著相关性。仅将视神经乳头颞侧象限的数据与视野进行比较并不能改善相关性。最佳的,即高度显著的相关性存在于视神经乳头参数与患者年龄之间。相关系数远低于其他已发表的数据。多种因素可能导致这些微弱的相关性:一方面是不同的视神经乳头形态,另一方面是局部或弥漫性视野缺损。在未经过选择的病例中,似乎无法预测给定视神经乳头的视野。两种方法都适用于随访,但并非所有视神经乳头的解剖形态都允许这样做。