Iester M, Mikelberg F S, Courtright P, Drance S M
Department of Opthalmology, University of British Columbia, Vancouver, Canada.
J Glaucoma. 1997 Apr;6(2):78-82.
We wished to determine whether a relationship exists between Heidelberg retina tomograph (HRT) parameters and the visual field indices.
One eye was randomly chosen from 59 normal patients [normal visual field and normal optic nerve head (ONH) and intraocular pressure (IOP) < 21 mm Hg], 64 ocular hypertensive patients (normal visual field and normal OHN and IOP > 22 mm Hg), 124 high-tension glaucoma patients (abnormal visual field and/or abnormal optic nerve and IOP > 22 mm Hg) and 47 low-tension glaucoma patients (abnormal visual field and or optic disc and IOP < 21 mm Hg). All the patients were examined with Humphrey Perimeter, program 30-2, and HRT. Findings were assessed by analysis of variance, Pearson's correlation coefficient, and multiple linear regression.
Among all subjects, we noted a statistically significant correlation (Pearson's r, p < 0.001) between cup area, cup/disc area ratio, rim area, rim volume, cup shape measure, and retinal nerve fiber layer cross-section area with mean deviation and corrected pattern SD. Multiple linear regression analysis demonstrated that rim area was the most important predictor of mean deviation and corrected pattern SD.
The presence of significant correlations between some HRT parameters, such as rim area and cup shape measure and visual field indices, suggests that these HRT parameters could be good indicators of the degree of glaucomatous ONH damage.
我们希望确定海德堡视网膜断层扫描仪(HRT)参数与视野指标之间是否存在关联。
从59名正常患者(视野正常、视神经乳头正常且眼压<21 mmHg)、64名高眼压症患者(视野正常、视神经乳头正常且眼压>22 mmHg)、124名高眼压性青光眼患者(视野异常和/或视神经异常且眼压>22 mmHg)以及47名低眼压性青光眼患者(视野异常和/或视盘异常且眼压<21 mmHg)中随机选取一只眼睛。所有患者均接受了Humphrey视野计30 - 2程序检查和HRT检查。通过方差分析、Pearson相关系数和多元线性回归对结果进行评估。
在所有受试者中,我们发现杯盘面积、杯盘面积比、盘沿面积、盘沿体积、杯盘形状测量值以及视网膜神经纤维层横截面积与平均偏差和校正模式标准差之间存在统计学显著相关性(Pearson相关系数r,p<0.001)。多元线性回归分析表明,盘沿面积是平均偏差和校正模式标准差的最重要预测指标。
一些HRT参数(如盘沿面积和杯盘形状测量值)与视野指标之间存在显著相关性,这表明这些HRT参数可能是青光眼性视神经乳头损害程度的良好指标。