Pérez Molina Anelys D, Gala González Angela, Rodríguez Barreras Maria E, Capó de Paz Virginia, Collazo Caballero Sonia, Fernández Andreu Carlos
Instituto De Medicina Tropical Pedro Kouri, Ciudad de La Habana, Cuba.
Rev Cubana Med Trop. 2007 May-Aug;59(2):119-26.
Cutaneous infection by histoplasmosis in Cuban HIV patients was researched. In a case series study, all HIV patients admitted to "Pedro Kouri" Institute from January 1st, 1992 to June 30th, 2003, who had been diagnosed with cutaneous histoplasmosis, were included. Of 44 patients with histoplasmosis, 52% (23 cases) developed the progressive disseminated form of histoplasmosis, which behaved as a subacute weakening disease. Young adults represented 56.5% and 82.6% were males mainly Caucasian (91.3%). Most of cases came from the Western provinces. Histoplasmosis was a marker disease in 39.1% of cases. CD4+ T-lymphocyte counting under 200 cell/mm3 was present in 78.9% of patients. Histoplasmosis seems to behave as an important marker disease for AIDs in seropositive patients. Serology was not the diagnosing method of choice for this cutaneous disease in AIDS patients.
对古巴艾滋病患者的组织胞浆菌病皮肤感染情况进行了研究。在一项病例系列研究中，纳入了1992年1月1日至2003年6月30日期间入住“佩德罗·库里”研究所且被诊断为皮肤组织胞浆菌病的所有艾滋病患者。在44例组织胞浆菌病患者中，52%（23例）发展为播散性进行型组织胞浆菌病，表现为亚急性衰弱性疾病。青年成年人占56.5%，82.6%为男性，主要是白种人（91.3%）。大多数病例来自西部省份。在39.1%的病例中，组织胞浆菌病是标志性疾病。78.9%的患者CD4 + T淋巴细胞计数低于200个细胞/mm³。组织胞浆菌病似乎是血清反应阳性患者艾滋病的一种重要标志性疾病。血清学检查并非艾滋病患者这种皮肤疾病的首选诊断方法。
