Institute of Internal Medicine, Siberian Branch of the Russian Academy of Medical Sciences, Novosibirsk, Russia.
Obes Facts. 2013;6(1):28-38. doi: 10.1159/000348549. Epub 2013 Feb 21.
To investigate whether bright light treatment can reduce body mass in overweight subjects irrespective of their seasonal (= light) dependence.
A crossover, placebo-controlled, randomized clinical trial was performed between November and April in Novosibirsk, Russia (55° N). The trial comprised a 3-week in-home session of morning bright light treatment using a device of light-emitting diodes and a 3-week placebo session by means of a deactivated ion generator, separated by an off-protocol period of at least 23 days. The number of placebo and light sessions was matched with respect to season. Data were obtained from 34 overweight women, aged 20-54 years, 10 were seasonal-dependent according to the Seasonal Pattern Assessment Questionnaire. Weekly measures included body weight, percentage body fat by bioimpedancemetry, and subjective scores (appetite, mood, energy levels).
Motivation and expectation towards weight loss were similar for the two intervention sessions. With light, compared to the placebo session, weight did not reduce significantly, but percentage fat, fat mass, and appetite were significantly lower (average fat reduction 0.35 kg). The latter two results remained significant after excluding seasonal-dependent subjects from the analysis. Irrespective of the type of intervention, seasonal-dependent subjects had greater weight and fat mass changes during treatment (decline p < 0.036) or between sessions (regain p < 0.003). Photoperiod (p = 0.0041), air temperature to a lesser extent (p = 0.012), but not sunshine (p = 0.29) was associated with the weight change (greater weight reduction if the second session was in spring).
Morning bright light treatment reduces body fat and appetite in overweight women and may be included in weight control programs.
研究在超重人群中，无论其季节性（光依赖）如何，光照治疗是否可以减轻体重。
在俄罗斯新西伯利亚（北纬 55°），于 11 月至 4 月进行了一项交叉、安慰剂对照、随机临床试验。该试验包括在家中进行为期 3 周的早晨光照治疗，使用发光二极管设备，以及为期 3 周的安慰剂治疗，通过协议外至少 23 天的间隔期。安慰剂和光照治疗的次数与季节相匹配。从 34 名年龄在 20-54 岁之间的超重女性中获得了数据，其中 10 名根据季节性模式评估问卷被归类为季节性依赖。每周测量包括体重、生物电阻抗法测量的体脂肪百分比以及主观评分（食欲、情绪、能量水平）。
对于两种干预措施，减肥的动机和期望相似。与安慰剂组相比，光照组体重没有显著减轻，但体脂肪百分比、脂肪量和食欲显著降低（平均脂肪减少 0.35 公斤）。排除季节性依赖组后，后两个结果仍然显著。无论干预类型如何，季节性依赖组在治疗期间（下降 p < 0.036）或治疗期间（恢复 p < 0.003）的体重和脂肪量变化更大。光周期（p = 0.0041）、空气温度（p = 0.012），但阳光（p = 0.29）与体重变化有关（如果第二次治疗在春季，则体重减轻更多）。
早晨光照治疗可减少超重女性的体脂肪和食欲，可纳入体重控制计划。
