研究经费。关于使用高致病性禽流感 H5N1 病毒进行研究的决策框架。
Research funding. A framework for decisions about research with HPAI H5N1 viruses.
机构信息
National Institutes of Health, Bethesda, MD 20892, USA.
出版信息
Science. 2013 Mar 1;339(6123):1036-7. doi: 10.1126/science.1236194. Epub 2013 Feb 21.
Abstract
The U.S. Department of Health and Human Services unveils a Framework for funding decisions about highly pathogenic avian influenza H5N1 research.
摘要
美国卫生与公众服务部公布了一个框架，用于资助高致病性禽流感 H5N1 研究的决策。
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本文引用的文献
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H5N1 virus: Transmission studies resume for avian flu.H5N1病毒：禽流感传播研究重启。
Nature. 2013 Jan 31;493(7434):609. doi: 10.1038/nature11858. Epub 2013 Jan 23.
2
Airborne transmission of influenza A/H5N1 virus between ferrets.雪貂之间甲型流感病毒 H5N1 的空气传播。
Science. 2012 Jun 22;336(6088):1534-41. doi: 10.1126/science.1213362.
3
Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets.实验性改造的流感 H5 HA 可使重组 H5 HA/H1N1 病毒在雪貂中通过呼吸道飞沫传播。
Nature. 2012 May 2;486(7403):420-8. doi: 10.1038/nature10831.
4
Pause on avian flu transmission studies.暂停禽流感传播研究。
Nature. 2012 Jan 20;481(7382):443. doi: 10.1038/481443a.
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