被低估的现象：偏头痛先兆期的高级皮质功能障碍。

Underestimated phenomena: higher cortical dysfunctions during migraine aura.

机构信息

Clinic of Neurology, Clinical Center of Serbia, Serbia.

出版信息

Cephalalgia. 2013 Jul;33(10):861-7. doi: 10.1177/0333102413476373. Epub 2013 Feb 19.

DOI:10.1177/0333102413476373

PMID:23430982

Abstract

INTRODUCTION

Aura occurs in 20-30% of patients with migraine. Some descriptions of aura go far beyond the most frequent visual and sensory symptoms, suggesting the involvement of different cortical areas. The aim of this prospective study was to evaluate the frequency and types of disorders of higher cortical functions (HCF) that occur during visual and/or sensory aura.

METHODS

We interviewed 60 patients with visual and/or sensory aura about HCF disorders of praxia, gnosia, memory, and speech, during aura. Patients were divided into two groups, with and without HCF disorders, and were compared in terms of demographic data and aura characteristics.

RESULTS

From all 60 patients, 65% reported at least one HCF disorder during aura. The patients with HCF disorders had longer-lasting auras (28.51 ± 16.39 vs. 19.76 ± 11.23, P = 0.016). The most common HCF disorders were motor dysphasia (82.05%) and dysnomia (30.74%). Motor dysphasia was more often reported by patients with visual as well as sensory aura ( P = 0.002). The number of HCF disorders correlated with the aura duration ( P = 0.003).

CONCLUSION

According to our results, HCF disorders during aura occur more often than previously thought. The aura duration has some influence on the HCF disorders.

摘要

简介

先兆在 20-30%的偏头痛患者中出现。一些先兆的描述远远超出了最常见的视觉和感觉症状，表明涉及不同的皮质区域。本前瞻性研究的目的是评估在视觉和/或感觉先兆期间发生的高级皮质功能（HCF）障碍的频率和类型。

方法

我们对 60 名有视觉和/或感觉先兆的患者进行了关于动作、认知、记忆和言语障碍的 HCF 障碍访谈，在先兆期间。患者被分为有和没有 HCF 障碍两组，并在人口统计学数据和先兆特征方面进行了比较。

结果

在所有 60 名患者中，65%在先兆期间报告至少有一种 HCF 障碍。有 HCF 障碍的患者的先兆持续时间更长（28.51 ± 16.39 与 19.76 ± 11.23，P = 0.016）。最常见的 HCF 障碍是运动性构音障碍（82.05%）和命名障碍（30.74%）。运动性构音障碍在有视觉和感觉先兆的患者中更为常见（P = 0.002）。HCF 障碍的数量与先兆持续时间相关（P = 0.003）。