Giordano Salvatore, Serra Gregorio, Dones Piera, Di Gangi Maria, Failla Maria Concetta, Iaria Chiara, Ricciardi Filippo, Pernice Lucia Maria, Pantaleo Dario, Cascio Antonio
Unita Operativa Complessa di Malattie Infettive, Palermo, Italy.
New Microbiol. 2013 Jan;36(1):97-101. Epub 2013 Jan 1.
This report describes a case of acute pancreatitis in a 2-year-old boy following rotavirus gastroenteritis. Its characteristics are analyzed and discussed in the light of another 4 cases of pancreatitis associated with rotavirus infection found through a systematic review of the international literature. None of the five children underwent surgery or was referred to an intensive care unit and all 5 children recovered with normalization of pancreatic enzymes within 5-10 days. The pathogenesis of this rare complication remains unsettled, and its actual incidence may be higher than reported. Although acute pancreatitis associated with rotavirus gastroenteritis seems to be a mild disease, attention must be paid by the pediatrician fearing possible complications. Rotavirus infection should be amended to the differential diagnosis panel of pancreatitis in toddlers.
本报告描述了一名2岁男童在轮状病毒胃肠炎后发生急性胰腺炎的病例。结合通过对国际文献进行系统回顾发现的另外4例与轮状病毒感染相关的胰腺炎病例,对其特征进行了分析和讨论。这5名儿童均未接受手术,也未被转入重症监护病房,所有5名儿童均在5 - 10天内康复,胰腺酶恢复正常。这种罕见并发症的发病机制尚不清楚,其实际发病率可能高于报道。虽然与轮状病毒胃肠炎相关的急性胰腺炎似乎是一种轻症疾病,但担心可能出现并发症的儿科医生必须予以关注。轮状病毒感染应纳入幼儿胰腺炎的鉴别诊断清单。