• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一篇关于雷特综合征及自闭症理论的综述。

A review of the Rett syndrome with a theory of autism.

作者信息

Olsson B, Rett A

机构信息

Ludwig Boltzmann-Institute for Research on Brain Damage in Children, Wien, Austria.

出版信息

Brain Dev. 1990;12(1):11-5. doi: 10.1016/s0387-7604(12)80166-5.

DOI:10.1016/s0387-7604(12)80166-5
PMID:2344005
Abstract

In a review of results of clinical observations, girls from 2:03 (yrs:mos) at stages III and IV of the Rett syndrome (RS) and autistic children from 4:01 with or without severe mental retardation were compared as to their behavioral traits. Signs of concordance between the extremely low mental, affective and motor developmental levels, such as in the expression of the eyes, are a prominent feature of RS, whereas signs of higher cortical functions that are in contrast with insufficient relations to objects, people and space are a prominent characteristic in autism. It is argued that insistence on sameness, avoidance of social stimuli and self-injurious stereotypies of autistic children are neurotic reactions based on their insufficient object relations. On the basis of the clinical findings a theory is proposed, according to which there exists a system for involuntary contributions to the affective engagement in perception, which is insufficiently developed in autism and in earlier stages of RS. Regarding its structure and function, it is analogous to the phylogenetically old extrapyramidal system and its necessary involuntary emotional contributions to all voluntary movements and postures.

摘要

在一项临床观察结果综述中,对患有雷特综合征(RS)III期和IV期、年龄为2岁零3个月的女孩,以及年龄为4岁零1个月、有或没有严重智力迟钝的自闭症儿童的行为特征进行了比较。极低的智力、情感和运动发育水平之间的一致性迹象,比如眼神的表达,是雷特综合征的一个突出特征,而与对物体、人和空间的联系不足形成对比的较高皮质功能迹象,则是自闭症的一个突出特点。有人认为,自闭症儿童坚持同一性、回避社会刺激和自我伤害性刻板行为是基于其客体关系不足的神经症反应。基于临床发现提出了一种理论,根据该理论,存在一个对感知中的情感投入进行非自愿贡献的系统,该系统在自闭症和雷特综合征的早期阶段发育不足。就其结构和功能而言,它类似于系统发生上古老的锥体外系及其对所有随意运动和姿势的必要非自愿情感贡献。

相似文献

1
A review of the Rett syndrome with a theory of autism.一篇关于雷特综合征及自闭症理论的综述。
Brain Dev. 1990;12(1):11-5. doi: 10.1016/s0387-7604(12)80166-5.
2
Behavioral observations concerning differential diagnosis between the Rett syndrome and autism.关于雷特综合征与自闭症鉴别诊断的行为观察
Brain Dev. 1985;7(3):281-9. doi: 10.1016/s0387-7604(85)80029-2.
3
Features of autism in Rett syndrome and severe mental retardation.雷特综合征和重度智力障碍中的自闭症特征。
J Autism Dev Disord. 2003 Aug;33(4):435-42. doi: 10.1023/a:1025066913283.
4
The role of stereotypies in overselectivity process in Rett syndrome.刻板动作在雷特综合征过度选择性过程中的作用。
Res Dev Disabil. 2009 Jan-Feb;30(1):136-45. doi: 10.1016/j.ridd.2008.01.003. Epub 2008 Mar 21.
5
Hand stereotypies distinguish Rett syndrome from autism disorder.手刻板动作可将雷特综合征与自闭症谱系障碍区分开来。
Mov Disord. 2012 Jul;27(8):1060-2. doi: 10.1002/mds.25057. Epub 2012 Jun 18.
6
Influence of eye movements on Rett stereotypies: evidence suggesting a stage-specific regression.眼球运动对雷特综合征刻板动作的影响:表明存在特定阶段退化的证据。
J Child Neurol. 1998 Apr;13(4):158-62. doi: 10.1177/088307389801300402.
7
Autistic disorder symptoms in Rett syndrome.雷特综合征的自闭症障碍症状。
Autism. 2009 Nov;13(6):567-81. doi: 10.1177/1362361309338184.
8
Disorganized rhythm and synchrony: early signs of autism and Rett syndrome.节律紊乱与同步性:自闭症和雷特综合征的早期迹象。
Brain Dev. 2005 Nov;27 Suppl 1:S25-S34. doi: 10.1016/j.braindev.2005.03.016. Epub 2005 Sep 22.
9
Rett syndrome: a comprehensive review of the literature.瑞特综合征:文献综述
Am J Ment Retard. 1991 Nov;96(3):275-90.
10
Pervasive disintegrative disorder: are Rett syndrome and Heller dementia infantilis subtypes?弥漫性瓦解障碍:雷特综合征和婴儿痴呆(海勒综合征)是其亚型吗?
Dev Med Child Neurol. 1989 Oct;31(5):609-16. doi: 10.1111/j.1469-8749.1989.tb04046.x.

引用本文的文献

1
Role of Genetics in the Etiology of Autistic Spectrum Disorder: Towards a Hierarchical Diagnostic Strategy.遗传学在自闭症谱系障碍病因学中的作用:迈向分层诊断策略
Int J Mol Sci. 2017 Mar 12;18(3):618. doi: 10.3390/ijms18030618.
2
Training communication abilities in Rett Syndrome through reading and writing.通过阅读和写作训练雷特综合征患者的沟通能力。
Front Psychol. 2013 Dec 6;4:911. doi: 10.3389/fpsyg.2013.00911. eCollection 2013.
3
Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders.组蛋白去乙酰化酶抑制在神经退行性疾病和精神疾病中的表观遗传靶点
Curr Opin Pharmacol. 2008 Feb;8(1):57-64. doi: 10.1016/j.coph.2007.12.002.
4
Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders.《自闭症诊断访谈修订版》:一份针对可能患有广泛性发育障碍个体的照料者的诊断访谈修订版本。
J Autism Dev Disord. 1994 Oct;24(5):659-85. doi: 10.1007/BF02172145.
5
Rett syndrome: a review of current knowledge.雷特综合征:当前知识综述
J Autism Dev Disord. 1991 Dec;21(4):381-406. doi: 10.1007/BF02206866.