Harrison D J, Webb P J
Royal National Orthopaedic Hospital, London, England.
Brain Dev. 1990;12(1):154-6. doi: 10.1016/s0387-7604(12)80200-2.
The Rett syndrome (RS) is associated with a neurological form of scoliosis. From 1985 we have instituted a postal survey of families with Rett girls. The prevalence of scoliosis in the survey population is 64%. The age at onset of scoliosis has a normal distribution about a peak age of 8 years, with 72% of cases occurring before age 8. The scoliosis in RS is typically a long thoracolumbar curvature that progresses rapidly in girls over the age of 10 years. Operative treatment is successful in reducing the curvature, preventing curve progression and improving spinal balance for sitting and walking. The 5 girls who walked pre-operatively are still able to do so.
瑞特综合征（RS）与神经源性脊柱侧弯有关。自1985年以来，我们对患有瑞特综合征女童的家庭进行了邮寄调查。调查人群中脊柱侧弯的患病率为64%。脊柱侧弯的发病年龄呈正态分布，峰值年龄约为8岁，72%的病例发生在8岁之前。瑞特综合征中的脊柱侧弯通常是长的胸腰段弯曲，在10岁以上的女孩中进展迅速。手术治疗在减少弯曲度、防止弯曲进展以及改善坐立和行走时的脊柱平衡方面是成功的。术前能行走的5名女孩术后仍然能够行走。
