Gillberg C, Terenius L, Hagberg B, Witt-Engerström I, Eriksson I
Child Neuropsychiatry Centre, University of Gothenburg, Sweden.
Brain Dev. 1990;12(1):88-92. doi: 10.1016/s0387-7604(12)80185-9.
Thirty-one children with autistic disorder, 8 with the Rett syndrome (RS), 2 with childhood disintegrative disorder and 5 with infantile spasms were compared with healthy adult controls with respect to cerebrospinal fluid (CSF) beta-endorphin levels. The autistic disorder and RS groups showed significantly lower values than the other groups. There were no age trends within the various groups. Further study of CSF beta-endorphins in these disorders and blindly examined age matched controls is warranted.
对31名患有自闭症谱系障碍的儿童、8名患有雷特综合征（RS）的儿童、2名患有儿童期瓦解性障碍的儿童和5名患有婴儿痉挛症的儿童，就脑脊液（CSF）β-内啡肽水平与健康成人对照组进行了比较。自闭症谱系障碍组和雷特综合征组的值显著低于其他组。各年龄组内均无年龄趋势。有必要对这些疾病中的脑脊液β-内啡肽以及经过盲法检查的年龄匹配对照组进行进一步研究。
