Baab D A, Oberg A, Lundström A
Department of Periodontics, University of Washington, Seattle 98195.
Arch Oral Biol. 1990;35(2):95-101. doi: 10.1016/0003-9969(90)90169-b.
Whether such individuals have different gingival blood flow and temperature responses to local cooling than age- and sex-matched healthy controls was tested. Ten patients with a history of localized juvenile periodontitis or rapidly progressive periodontitis were selected from a periodontal clinic and matched with healthy controls. Gingival blood flow and temperature were monitored continuously before and after cooling via a twin probe placed in the gingival sulcus on the buccal of tooth No. 26. Blood flow was assessed by laser Doppler flowmetry and temperature by a small metal thermistor. Resting values were first recorded for 5 min, followed by 3 min of cooling to 19 degrees C by a gentle stream of cool air, then 12 min of rewarming was allowed. This protocol was repeated twice. Blood flow changes were analysed as the slope of the line formed between the last 2 min of cooling and the last 2 min of rewarming; temperature curves were analysed by a least-squares curve fit of a bi-exponential function. Patients with localized juvenile periodontitis and rapidly progressive periodontitis had similar rewarming temperature curves, but significantly faster blood flow recovery curves than controls (p less than 0.03). Thus, gingival blood flow in young periodontitis patients recovered more rapidly after local cooling than in healthy controls.
测试了这些个体与年龄和性别匹配的健康对照相比，对局部冷却是否有不同的牙龈血流和温度反应。从牙周诊所挑选出10名有局限性青少年牙周炎或快速进展性牙周炎病史的患者，并与健康对照进行匹配。通过放置在26号牙颊侧牙龈沟内的双探头，在冷却前后连续监测牙龈血流和温度。血流通过激光多普勒血流仪评估，温度通过小型金属热敏电阻测量。首先记录5分钟的静息值，然后用一股冷空气轻柔吹拂3分钟，将温度降至19摄氏度，接着允许12分钟的复温。该方案重复两次。血流变化分析为冷却最后2分钟与复温最后2分钟之间形成的直线斜率；温度曲线通过双指数函数的最小二乘曲线拟合进行分析。局限性青少年牙周炎和快速进展性牙周炎患者有相似的复温温度曲线，但血流恢复曲线明显比对照组快（p小于0.03）。因此，年轻牙周炎患者局部冷却后牙龈血流的恢复比健康对照更快。
