Lim B H, Mahmood T A, Lees D A
Department of Obstetrics and Gynaecology, Raigmore Hospital, Inverness, Scotland.
Asia Oceania J Obstet Gynaecol. 1990 Mar;16(1):21-5. doi: 10.1111/j.1447-0756.1990.tb00210.x.
Experience with the use of Gemeprost pessaries (prostaglandin E1 analogue), in a group of 60 consecutive patients for second trimester termination in a Scottish District General Hospital, is presented. Gestation ranged from 12 to 20 weeks; there were 29 nulliparous (48%) and 31 (52%) multiparous women. Fifty-seven (95%) aborted within 36 hours; 29 (48%) aborted completely and did not require further uterine curettage. Nulliparous patients required more pessaries and the abortion was more often incomplete. Side effects were minimal. There were no serious problems; and antiemetics were required by 17% and parenteral analgesics by 13% of patients.
本文介绍了在苏格兰一家地区综合医院，对连续60例中期妊娠终止患者使用吉美前列素阴道栓剂（前列腺素E1类似物）的经验。孕周为12至20周；其中初产妇29例（48%），经产妇31例（52%）。57例（95%）在36小时内流产；29例（48%）完全流产，无需进一步刮宫。初产妇需要更多栓剂，且流产不全的情况更常见。副作用极小。未出现严重问题；17%的患者需要使用止吐药，13%的患者需要使用注射用镇痛药。
