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90 岁人群的体重指数、腰围和腰臀比与瘦素有关吗?

Are body mass index, waist circumference and waist-to-hip ratio associated with leptin in 90-year-old people?

机构信息

Gerontology Research Center and School of Health Sciences, University of Tampere, Tampere, Finland.

出版信息

Eur J Clin Nutr. 2013 Apr;67(4):420-2. doi: 10.1038/ejcn.2013.39. Epub 2013 Feb 27.

DOI:10.1038/ejcn.2013.39
PMID:23443829
Abstract

Data on how body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) are associated with body fat in the oldest-old people are scarce. The purpose of this study was to examine if BMI, WC or WHR are associated with leptin, a biological surrogate measure of body fat in 90-year-old people. The data comes from the Vitality 90+ Study, a prospective population-based study of people living in Tampere, Finland. BMI, WC, WHR and plasma concentration of leptin were available for 160 women and 54 men aged 90 years. BMI and WC had a strong significant positive association with leptin both in women and in men, but WHR was associated with leptin only in men. In conclusion, based on the circulating level of leptin, BMI and WC, and WHR in men, reflect body fat in 90-year-old people, but WHR seems to be a poor indicator of body fat in 90-year-old women.

摘要

关于身体质量指数(BMI)、腰围(WC)和腰臀比(WHR)与最年长人群体脂肪之间的关联的数据很少。本研究的目的是检验 BMI、WC 或 WHR 是否与瘦素有关,瘦素是体脂肪的生物替代测量指标。数据来自于活力 90+研究,这是一项针对芬兰坦佩雷市居民的前瞻性人群基础研究。160 名女性和 54 名 90 岁的男性提供了 BMI、WC、WHR 和瘦素的血浆浓度。BMI 和 WC 与女性和男性的瘦素均有很强的显著正相关,但 WHR 仅与男性的瘦素相关。总之,基于循环瘦素水平,BMI、WC 和 WHR 反映了 90 岁男性的体脂肪,但 WHR 似乎是 90 岁女性体脂肪的一个较差指标。

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