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为发展中国家设计的低成本、简单的宫腔内人工授精程序,使用未洗涤的离心丈夫精液。

Low cost, simple, intrauterine insemination procedure with unwashed centrifuged husband's sperm for developing countries.

作者信息

Mve Rose Nsa Ada, Formigli Leonardo

机构信息

Centre de Procréation Médicalement Assistée "Ibekélia Marie" BP 2956, Libreville, Gabon.

出版信息

Afr J Reprod Health. 2012 Dec;16(4):175-9.

Abstract

There is an increased need for low cost procedures in treating infertility particularly in developing countries. Intrauterine insemination was used long before the advent of in vitro fertilization. During the last 30 years however, intrauterine insemination has evolved with the introduction of ovulation stimulating protocols and sperm preparation methods taken from assisted reproduction techniques. Costs have risen, but the success rate has not risen to the same extent. We have therefore developed a quite simple intrauterine insemination technique which may be performed in developing countries, without the need of sophisticated equipment, costly materials, media, or disposable insemination catheters; it is quite inexpensive and may be performed by trained staff, such as nurses or midwives. 20 to 27% (depending on the aetiology of their reproduction problem) of the couples remained clinically pregnant after an average of 3.5 to 3.8 intrauterine inseminations procedures.

摘要

在治疗不孕症方面,尤其是在发展中国家,对低成本程序的需求日益增加。早在体外受精出现之前,宫内授精就已被使用。然而,在过去30年中,随着排卵刺激方案的引入以及从辅助生殖技术中借鉴的精子制备方法,宫内授精得到了发展。成本有所上升,但成功率并未相应提高。因此,我们开发了一种非常简单的宫内授精技术,该技术可在发展中国家实施,无需复杂设备、昂贵材料、培养基或一次性授精导管;成本相当低廉,可由经过培训的人员(如护士或助产士)进行操作。平均经过3.5至3.8次宫内授精程序后,20%至27%(取决于其生殖问题的病因)的夫妇实现了临床妊娠。

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