Department of Gastroenterology, Center for Inflammatory Bowel Disease, Saint Panteleimon General Hospital, Nicea, Greece.
Expert Rev Gastroenterol Hepatol. 2013 Mar;7(3):225-38. doi: 10.1586/egh.13.4.
The role of psychological distress and personality as predisposing factors for the development of inflammatory bowel disease (IBD) remains controversial. Attempts to investigate the role of psychological factors in IBD exhibited rather conflicting results. Among the studies concerning the effects of stress or depression on the course of IBD, the majority suggest that stress worsened IBD, the rest giving either negative or inconclusive results. However, application of strategies, including avoidance of coping and training patients in problem solving or emotion-oriented, could influence the course of IBD. Large controlled clinical trials are needed in order to clarify the impact of psychological interventions on the quality of life and the course of disease.
心理困扰和人格作为炎症性肠病（IBD）发病的诱发因素的作用仍存在争议。尝试研究心理因素在 IBD 中的作用，结果显示存在较多矛盾。在研究压力或抑郁对 IBD 病程的影响的研究中，大多数研究表明压力会加重 IBD，其余研究结果则为负面或不确定。然而，采用一些策略，包括避免应对以及对患者进行解决问题或情绪导向的训练，可能会影响 IBD 的病程。需要进行大规模的对照临床试验，以明确心理干预对生活质量和疾病病程的影响。
