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[角膜内皮移植术(DMEK)、深板层角膜内皮移植术(DSAEK)和准分子激光角膜切削术(DALK)后的免疫反应]

[Immune reactions after DMEK, DSAEK and DALK].

作者信息

Steven P, Hos D, Heindl L M, Bock F, Cursiefen C

机构信息

Zentrum für Augenheilkunde, Universität zu Köln. Kerpener Strasse 62, Koln.

出版信息

Klin Monbl Augenheilkd. 2013 May;230(5):494-9. doi: 10.1055/s-0032-1328257. Epub 2013 Feb 27.

DOI:10.1055/s-0032-1328257
PMID:23446757
Abstract

PURPOSE

The aim of this study is to describe incidence, diagnosis and therapy for endothelial immune reactions after modern lamellar corneal transplantat surgery (DMEK, DSAEK, DALK).

METHODS

A PubMed-based literature review and our own clinical and experimental data are evaluated.

RESULTS

There is no longer an endothelial immune reaction after DALK for keratoconus. DMEK significantly reduces the risk for endothelial immune reactions after surgery for Fuchs dystrophy.

CONCLUSIONS

Modern lamellar corneal transplant techniques such as DALK and DMEK have nearly abolished the risk for endothelial immune reactions in the avascular recipient bed.

摘要

目的

本研究旨在描述现代板层角膜移植手术(DMEK、DSAEK、DALK)后内皮免疫反应的发生率、诊断和治疗。

方法

对基于PubMed的文献综述以及我们自己的临床和实验数据进行评估。

结果

圆锥角膜行DALK术后不再发生内皮免疫反应。DMEK显著降低了富克斯营养不良手术后内皮免疫反应的风险。

结论

DALK和DMEK等现代板层角膜移植技术几乎消除了无血管受体床中内皮免疫反应的风险。

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