Semenova-Kobzar' R A, Iudin V M, Kushko L Ia, Iakhimovich L V, Berezhnaia N M
Eksp Onkol. 1990;12(3):50-2.
Alternative principles of regional IL-2-dependent adoptive immunocytotherapy of malignant tumours are suggested. Regional adoptive immunocytotherapy consists in the administration of the short-term IL-2 treated lymphocytes of the lymph nodes removed from the tumour which have tumour-associated suppressor activity and spleen cells after elimination of cells with the immunosuppressive activity.
提出了恶性肿瘤局部白介素-2依赖的过继免疫细胞疗法的替代原则。局部过继免疫细胞疗法包括给予经短期白介素-2处理的、取自肿瘤部位且具有肿瘤相关抑制活性的淋巴结淋巴细胞,以及去除具有免疫抑制活性的细胞后的脾细胞。