Köchel Angelika, Leutgeb Verena, Schienle Anne
1Department of Clinical Psychology, University of Graz, Austria.
J Child Neurol. 2014 Apr;29(4):459-68. doi: 10.1177/0883073813476139. Epub 2013 Feb 28.
This event-related potential study focused on neural correlates of inhibitory affective control in attention-deficit hyperactivity disorder (ADHD). Sixteen boys with ADHD and 16 healthy boys underwent an emotional Go/NoGo task with pictures of facial expressions from the categories anger, sadness, happiness, and neutral. The participants were instructed to execute or withhold a motor response to specific emotions. Patients relative to controls displayed a severe impairment in response inhibition toward anger cues, which was accompanied by a reduced P300 amplitude (positive voltage deflection about 300 ms after picture onset). The control group showed a P300 differentiation of the affective categories that was absent in the ADHD group. The pronounced anger-processing deficit in ADHD patients might be linked to their interpersonal difficulties and should be addressed in psychotherapy.
这项与事件相关的电位研究聚焦于注意力缺陷多动障碍（ADHD）中抑制性情感控制的神经关联。16名患有ADHD的男孩和16名健康男孩参与了一项情绪Go/NoGo任务，任务中呈现愤怒、悲伤、快乐和中性这几类面部表情的图片。参与者被要求对特定情绪执行或抑制运动反应。与对照组相比，患者对愤怒线索的反应抑制存在严重受损，同时伴有P300波幅降低（图片呈现后约300毫秒的正向电压偏转）。对照组显示出情感类别之间的P300差异，而ADHD组则没有。ADHD患者明显的愤怒处理缺陷可能与他们的人际困难有关，在心理治疗中应予以关注。
