Sreehariprasad A V, Krishnappa R, Chikaraddi B Santosh, Veerendrakumar K
Department of Head and Neck Oncosurgery, Kidwai Memorial Institute of Oncology, Bangalore, India.
Indian J Surg Oncol. 2012 Mar;3(1):4-7. doi: 10.1007/s13193-012-0135-5. Epub 2012 Mar 17.
Hypopharyngeal cancers are uncommon. The management of advanced hypopharyngeal carcinomas has been a difficult problem. Surgical resection has been more successful. While many surgical methods have been used and reported pharyngolaryngo esophagectomy with gastric pull up remains the best option. This study documents our experience with patients who underwent total pharyngolaryngoesophagectomy with immediate gastric pull-up for advanced carcinoma hypopharynx. The clinical data of 17 patients treated with pharyngo-laryngo-esophagectomy for advanced carcinoma of the hypopharynx between 2001 and 2004 was analyzed. All patients had advanced disease and required a gastric pull-up for reconstruction. Data obtained included age, sex, site, stage, post op complication, duration of follow up, recurrence & survival. Average age was 37.7 years and ranged from 27 to 56 years. There were 13 female patients and 4 male patients .13 patients presented with postcricoid tumours and 4 with posterior pharyngeal wall tumors, 13 patients presented with stage 3 tumors and 4 patients presented with stage 4 tumors. Wound infection was present in 2 patients (11.7%), anastomotic leak in 1(5.8%), hypocalcemia in 1(5.8%) and malignant pleural effusion in 1 patient (5.8%). Local recurrence occurred in 1(5.8%) while nodal recurrence occurred in 5(29.4%) patient. The average over all survival in our study was 19.5 months and ranged from 2 to 101 months. The gastric pull-up operation is a useful and effective method for the immediate reconstruction of the advanced hypopharyngeal malignancy.
下咽癌并不常见。晚期下咽癌的治疗一直是个难题。手术切除更为成功。虽然已经使用了多种手术方法并进行了报道,但胃上提咽食管切除术仍是最佳选择。本研究记录了我们对晚期下咽癌患者行全咽食管切除术并立即进行胃上提术的经验。分析了2001年至2004年间17例因晚期下咽癌接受咽食管切除术患者的临床资料。所有患者均为晚期疾病,需要进行胃上提术重建。获得的数据包括年龄、性别、部位、分期、术后并发症、随访时间、复发情况和生存率。平均年龄为37.7岁,范围在27至56岁之间。有13例女性患者和4例男性患者。13例患者表现为环状软骨后肿瘤,4例表现为咽后壁肿瘤,13例患者为3期肿瘤,4例患者为4期肿瘤。2例患者出现伤口感染(11.7%),1例出现吻合口漏(5.8%),1例出现低钙血症(5.8%),1例患者出现恶性胸腔积液(5.8%)。1例患者出现局部复发(5.8%),5例患者出现淋巴结复发(29.4%)。我们研究中的总体平均生存期为19.5个月,范围在2至101个月之间。胃上提术是晚期下咽恶性肿瘤即刻重建的一种有用且有效的方法。