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消化道姑息性支架置入术:单中心病例系列。

Palliative stenting of the digestive tract: a case series of a single centre.

机构信息

Department of Internal Medicine and Gastroenterology, Zaans Medical Centre Zaandam, The Netherlands.

出版信息

J Gastrointest Oncol. 2013 Mar;4(1):14-9. doi: 10.3978/j.issn.2078-6891.2012.045.

DOI:10.3978/j.issn.2078-6891.2012.045
PMID:23450097
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3562623/
Abstract

BACKGROUND AND AIM

Obstruction of the gastrointestinal tract due to cancer can be treated with stenting. The aim was to review the local experience with endoscopic stenting. All patients treated with stenting in a ten years period from 2001-2010 were studied.

RESULTS

Fifty one patients received 57 stents because of oesophageal cancer. Mean survival after stent placement was 141 days. No case of perforation occurred. In nine cases (17%) clogging with food occurred. Tumour overgrowth was noted in four cases. Twenty four patients received 28 stents in their colon or rectum. The stents were placed in the rectum (n=6), the sigmoid (n=14), the descending colon (n=1), and the transverse colon (n=3). Mean survival was 276 days. Perforation did not occur. Tumour ingrowth was seen in two patients. One patient received a second stent. Dislocation occurred in two cases. There were two cases of clogging (8%) by stool. Fourteen patients received a total of 18 stents because of obstructing stomach cancer. Mean survival after placement was 121 days. There was no perforation, one case of clogging, and four cases of tumour ingrowth. Eight patients had stent placement in their duodenum. Mean survival after stent placement was 84 days. No perforation or clogging occurred. But three cases of tumour ingrowth were seen.

CONCLUSIONS

The present series shows that placement of expandable stents in the digestive tract in normal daily practice is feasible, safe, with a low number of complications, and provides good palliation for their remaining life.

摘要

背景与目的

癌症引起的胃肠道梗阻可以通过支架治疗。本研究旨在回顾内镜下支架置入的局部经验。

方法

研究了 2001 年至 2010 年十年间接受支架治疗的所有患者。

结果

51 例患者因食管癌接受了 57 个支架治疗。支架置入后的平均生存时间为 141 天。无穿孔发生。9 例(17%)发生食物堵塞。4 例出现肿瘤过度生长。24 例患者的结肠或直肠共置入 28 个支架。支架分别置于直肠(n=6)、乙状结肠(n=14)、降结肠(n=1)和横结肠(n=3)。平均生存时间为 276 天。无穿孔发生。2 例出现肿瘤向腔内生长。1 例患者再次置入支架。2 例发生支架移位。2 例(8%)发生粪便堵塞。14 例患者因胃恶性肿瘤梗阻共接受 18 个支架治疗。支架置入后的平均生存时间为 121 天。无穿孔、1 例堵塞和 4 例肿瘤向腔内生长。8 例患者在十二指肠中放置了支架。支架置入后的平均生存时间为 84 天。无穿孔或堵塞发生,但有 3 例出现肿瘤向腔内生长。

结论

本系列研究表明,在日常实践中,在消化道内放置可扩张支架是可行的、安全的,并发症少,并能为患者的剩余生命提供良好的姑息治疗。

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Comparison of 2 expandable stents for malignant esophageal disease: a randomized controlled trial.比较 2 种可扩张支架治疗恶性食管疾病:一项随机对照试验。
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Fully covered removable nitinol self-expandable metal stents (SEMS) in malignant strictures of the esophagus: a multicenter analysis.完全覆膜可回收镍钛形状记忆合金支架(SEMS)治疗食管恶性狭窄:多中心分析。
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Safety and efficacy of a new non-foreshortening nitinol stent in malignant gastric outlet obstruction (DUONITI study): a prospective, multicenter study.新型非短缩镍钛诺支架治疗恶性胃出口梗阻的安全性和有效性(DUONITI 研究):一项前瞻性、多中心研究。
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