Xing Xian-dong, Zhang Qian, Feng Feng, Liu Wen-yuan
Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China.
Zhong Yao Cai. 2012 Sep;35(9):1429-31.
To study the chemical constituents from the stems of Ilex pubescens Hook. et Am.
The chemical constituents were isolated and purified by various column chromatographic methods with diatomite, silica gel, ODS and Sephadex LH-20. Their structures were identified on physical properties and spectroscopic methods.
Nine compounds were isolated and determined as luteolin(1), quercetin(2), hyperoside(3), rutin(4), 1, 5-dihydroxy-3-methyl-anthraquinone(5),3,5-dimethoxy-4-hydroxy-benzoic acid-1-O-beta-D-glucoside(6), hexadecanoic acid(7), stearic acid(8), n-tetratriacontanol(9), respectively.
All the compounds are isolated from this plant for the first time, and compounds 5 and 6 are isolated from this genus for the first time.
