Bodensteiner J, Gay C T
Department of Neurology, West Virginia University School of Medicine, Morgantown 26506.
J Child Neurol. 1990 Apr;5(2):166-8. doi: 10.1177/088307389000500221.
Colpocephaly has been described as the persistence of the fetal configuration of the lateral ventricles. The pathologic picture is characterized by multiple features of disturbed or arrested development of the brain, which results in diminished thickness of the cerebral white matter in the posterior portion of the centrum semiovale, giving rise to large occipital horns of the lateral ventricles. This ventricular configuration allows the clinician to suspect the presence of this developmental disturbance utilizing computed tomographic images. In this paper, we present a case that demonstrates that not every patient with enlargement of the posterior horns of the lateral ventricles has the underlying developmental abnormalities that constitute colpocephaly as described by Yakovlev and Wadsworth. Furthermore, we point out the difficulties that can arise in the attempt to make a diagnosis of a pathologically defined condition on the basis of neuroimaging results alone.
脑室后角扩大被描述为侧脑室胎儿形态的持续存在。病理表现的特征是大脑发育紊乱或停滞的多种特征，这导致半卵圆中心后部的脑白质厚度减小，从而形成侧脑室的大枕角。这种脑室形态使临床医生能够利用计算机断层扫描图像怀疑存在这种发育障碍。在本文中，我们报告了一例病例，该病例表明并非每个侧脑室后角扩大的患者都存在如雅科夫列夫和沃兹沃思所描述的构成脑室后角扩大的潜在发育异常。此外，我们指出仅根据神经影像学结果试图诊断病理定义的疾病时可能出现的困难。
