Herskowitz J, Rosman N P, Wheeler C B
Neurology. 1985 Nov;35(11):1594-8. doi: 10.1212/wnl.35.11.1594.
Colpocephaly is an anatomic finding in the brain manifested by occipital horns that are disproportionately enlarged in comparison with other parts of the lateral ventricles. It has been considered to result from localized outpocketing of the ventricular cavity due to failure of thickening of overlying brain. Four new cases are presented here, including a child of near-normal development who appears to be the first reported case of colpocephaly with an associated chromosomal anomaly. Our patients support the view that colpocephaly is a disorder of diverse causation that can arise from a variety of degenerative or encephaloclastic insults to the developing brain.
脑室后角异常增宽是一种脑部解剖学表现，其枕角相对于侧脑室的其他部分不成比例地增大。它被认为是由于覆盖大脑增厚失败导致脑室腔局部向外膨出所致。本文报告了4例新病例，其中1例发育接近正常的儿童似乎是首例报道的伴有染色体异常的脑室后角异常增宽病例。我们的患者支持这样一种观点，即脑室后角异常增宽是一种病因多样的疾病，可由发育中大脑的各种退行性或破坏性损伤引起。
