KU Leuven, Animal Physiology and Neurobiology, Naamsestraat 59, P.O. Box 2465, Leuven, Belgium.
Gen Comp Endocrinol. 2013 Jul 1;188:137-43. doi: 10.1016/j.ygcen.2013.02.014. Epub 2013 Feb 27.
In many animal species, copulation elicits a number of physiological and behavioral changes in the female partner. In Drosophila melanogaster, the main molecular effector of these physiological responses has been identified as sex peptide (SP). The sex peptide receptor (SPR) has been characterized and recently, its activation by Drosophila myoinhibiting peptides (MIPs)-in addition to SP-has been demonstrated. The myoinhibiting peptides are members of a conserved peptide family, also known as B-type allatostatins, which generally feature the C-terminal motif -WX6Wamide.
在许多动物物种中，交配会引起雌性伴侣的一系列生理和行为变化。在黑腹果蝇中，这些生理反应的主要分子效应物已被确定为性肽（SP）。性肽受体（SPR）已被表征，最近，除了 SP 之外，还证明了其被果蝇肌抑制肽（MIPs）激活。肌抑制肽是一个保守肽家族的成员，也称为 B 型脑肠肽，其通常具有 C 末端基序 -WX6Wamide。
