Petrini C
Italian National Institute of Health, Rome, Italy.
Clin Ter. 2013;164(1):e53-61. doi: 10.7417/CT.2013.1522.
There are many ways of interpreting the notion of "innovation" with reference to therapeutics. The term is generally given a wide meaning, encompassing anything that brings something new. From the ethical point of view the definition of "innovation" is of key importance, for example when dealing with a major problem such as the evaluation of protocols that propose "innovative" therapies. There is currently debate as to whether this should be accomplished using the same procedures typically applied to experimental research protocols, or by following quite different procedures when "innovation" is involved. The present article offers an overview of the notion of "innovation" in the context of biomedical research, together with some considerations and proposals for evaluating it from the ethical viewpoint.
关于治疗学，有许多种解释“创新”概念的方式。这个术语通常具有广泛的含义，涵盖任何带来新事物的东西。从伦理角度来看，“创新”的定义至关重要，例如在处理诸如评估提出“创新”疗法的方案这样的重大问题时。目前存在争议的是，这是应该使用通常应用于实验研究方案的相同程序来完成，还是在涉及“创新”时遵循截然不同的程序。本文概述了生物医学研究背景下的“创新”概念，并从伦理角度提出了一些评估它的思考和建议。
