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罕见乳腺恶性肿瘤亚型:细胞学、组织学及免疫组化相关性研究

Rare Breast Malignancy Subtypes: A Cytological, Histological, and Immunohistochemical Correlation.

作者信息

Kaur Manmeet, Tiwana Kanwardeep Kaur, Singla Nisha

机构信息

Department of Pathology, GGS Medical College and Hospital, Faridkot, Punjab, India.

出版信息

Niger J Surg. 2019 Jan-Jun;25(1):70-75. doi: 10.4103/njs.NJS_27_18.

DOI:10.4103/njs.NJS_27_18
PMID:31007516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6452754/
Abstract

BACKGROUND

Breast malignancies encompass various subtypes which differ in their clinical presentations, outcomes, and response to the treatment regimens. Thus, a proper histological diagnosis and a special mention of the rare histologic subtypes are required to formulate clear recommendations of their treatment protocols.

MATERIALS AND METHODS

This is a 1-year retrospective study highlighting the rarely encountered subtypes on the mastectomy specimens received.

RESULTS

We encountered only 11 rare cases out of the total 153 mastectomy specimens received. The rare subtypes were as follows mucinous cystadenocarcinoma (0.6%), mucinous carcinoma (0.6%), dermatofibrosarcoma protuberans (0.6%), Squamous cell carcinoma (0.6%), papillary carcinoma (2.6%), medullary carcinoma (0.6%), and malignant mesenchymal tumor (1.3%).

CONCLUSION

Our data suggest that these variants are distinct clinicopathological entities with a unique hormonal receptor status. Scant information is available on the rare breast tumor subtypes.

摘要

背景

乳腺恶性肿瘤包含多种亚型,它们在临床表现、预后以及对治疗方案的反应方面存在差异。因此,需要进行恰当的组织学诊断,并特别提及罕见的组织学亚型,以便制定明确的治疗方案建议。

材料与方法

这是一项为期1年的回顾性研究,重点关注所接收的乳房切除标本中罕见的亚型。

结果

在总共153份接收的乳房切除标本中,我们仅遇到11例罕见病例。罕见亚型如下:黏液性囊腺癌(0.6%)、黏液癌(0.6%)、隆突性皮肤纤维肉瘤(0.6%)、鳞状细胞癌(0.6%)、乳头状癌(2.6%)、髓样癌(0.6%)和恶性间叶性肿瘤(1.3%)。

结论

我们的数据表明,这些变体是具有独特激素受体状态的不同临床病理实体。关于罕见乳腺肿瘤亚型的信息很少。

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Oncologist. 2014 Aug;19(8):805-13. doi: 10.1634/theoncologist.2014-0108. Epub 2014 Jun 26.
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Primary mucinous cystadenocarcinoma of the breast with endocervical-like mucinous epithelium.乳腺原发性黏液囊腺癌,伴宫颈内膜样黏液上皮。
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Primary Mucinous Cystadenocarcinoma of the Breast: Cytologic Finding and Expression of MUC5 Are Different from Mucinous Carcinoma.乳腺原发性黏液性囊腺癌:细胞学表现及MUC5表达与黏液癌不同。
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Solid papillary carcinoma of the breast: a pathologically and clinically distinct breast tumor.乳腺实性乳头状癌:一种在病理和临床方面均有独特表现的乳腺肿瘤。
Arch Pathol Lab Med. 2012 Oct;136(10):1308-11. doi: 10.5858/arpa.2011-0227-RS.
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Malignant Mesenchymal Tumor of the Breast: Primary Chondrosarcoma.乳腺恶性间叶肿瘤:原发性软骨肉瘤
Breast Care (Basel). 2009;4(2):101-103. doi: 10.1159/000212101. Epub 2009 Apr 24.
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Mucinous Cystadenocarcinoma of the Breast with Estrogen Receptor Expression: A Case Report and Review of the Literature.伴有雌激素受体表达的乳腺黏液性囊腺癌:一例报告及文献复习
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