Milman N, Selroos O
Department of Pulmonary Medicine, Gentofte Hospital, Copenhagen, Denmark.
Sarcoidosis. 1990 Mar;7(1):50-7.
The review is based on studies from Denmark, Finland, Norway and Sweden during 1950-1982. In general sarcoidosis was slightly more frequent in females than in males, especially after 40 years of age. The majority of cases were diagnosed before 35 years; 59% had symptoms, 41% were found by chance. Radiological stage I was present in 50%, stage II in 35%, and stage III-IV in 14%. The prevalence was age dependent with maximum between 18-35 years, varying from 8-102/10(5) examined persons in Finland to 27 in Norway and 64 in Sweden. The incidence was likewise age related, being highest in 18- to 20-years-old males (57/10(5) examined persons/year); overall incidence varied from 14-15/10(5) examined persons/year in Denmark, Finland and Norway to 24 in Sweden. No definite change in incidence figures has occurred. The accumulated lifetime risk of acquiring sarcoidosis was identical in the two sexes up to 45 years of age, and then increased in females; at 65 years the risk was 1.6% in females and 1.2% in males based on the population examined.
该综述基于1950年至1982年间丹麦、芬兰、挪威和瑞典的研究。一般来说，结节病在女性中比在男性中略为常见，尤其是在40岁以后。大多数病例在35岁之前被诊断出来；59%有症状，41%是偶然发现的。放射学分期I期占50%，II期占35%，III-IV期占14%。患病率与年龄有关，在18至35岁之间最高，芬兰每10（5）名受检者中患病率为8至102例，挪威为27例，瑞典为64例。发病率同样与年龄相关，在18至20岁男性中最高（每年每10（5）名受检者中有57例）；丹麦、芬兰和挪威的总体发病率为每年每10（5）名受检者中有14至15例，瑞典为24例。发病率数字没有明显变化。在45岁之前，两性患结节病的累积终生风险相同，之后女性风险增加；根据受检人群计算，65岁时女性风险为1.6%，男性为1.2%。
