Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.
J Clin Hypertens (Greenwich). 2013 Mar;15(3):147-53. doi: 10.1111/jch.12062. Epub 2013 Jan 14.
This paper provides recommendations on the treatment of orthostatic hypotension (OH) as reviewed by the American Society of Hypertension. It focuses on recent reports on the evaluation and management of OH and provides practical advice for clinicians on how to screen, diagnose, and treat patients using behavioral, nonpharmacologic, and pharmacologic strategies. The authors also provide a stepwise approach on how to apply new findings to successfully control OH and reduce the risk of syncope and falls in these patients. Treatment of OH is also discussed in special situations such as in hypertensive and hospitalized patients. It should be noted, however, that research in this area is mostly limited to studies in small numbers of patients. Unfortunately, the trials of the type needed to develop evidence-based guidelines are not available for this condition.
本文提供了美国高血压学会对直立性低血压（OH）治疗的建议。它侧重于最近关于 OH 的评估和管理的报告，并为临床医生提供了使用行为、非药物和药物策略进行筛查、诊断和治疗患者的实用建议。作者还提供了一种逐步的方法，说明如何应用新的发现成功控制 OH，并降低这些患者晕厥和跌倒的风险。在特殊情况下，如高血压和住院患者，也会讨论 OH 的治疗。然而，应当指出，该领域的研究主要限于少数患者的研究。不幸的是，对于这种情况，还没有开展基于证据的指南所需的那种类型的试验。
