Australian Research Council Centre of Excellence in Plant Energy Biology, Australian National University Canberra, ACT, Australia.
Front Plant Sci. 2013 Mar 1;4:32. doi: 10.3389/fpls.2013.00032. eCollection 2013.
The cytosolic ribosomal proteome of Arabidopsis thaliana has been studied intensively by a range of proteomics approaches and is now one of the most well characterized eukaryotic ribosomal proteomes. Plant cytosolic ribosomes are distinguished from other eukaryotic ribosomes by unique proteins, unique post-translational modifications and an abundance of ribosomal proteins for which multiple divergent paralogs are expressed and incorporated. Study of the A. thaliana ribosome has now progressed well beyond a simple cataloging of protein parts and is focused strongly on elucidating the functions of specific ribosomal proteins, their paralogous isoforms and covalent modifications. This review summarises current knowledge concerning the Arabidopsis cytosolic ribosomal proteome and highlights potentially fruitful areas of future research in this fast moving and important area.
拟南芥细胞质核糖体蛋白组已通过一系列蛋白质组学方法进行了深入研究，现在是最具特征的真核核糖体蛋白组之一。植物细胞质核糖体与其他真核核糖体的区别在于其独特的蛋白质、独特的翻译后修饰以及大量核糖体蛋白，这些核糖体蛋白表达和包含多个不同的基因。对拟南芥核糖体的研究现在已经远远超出了对蛋白质部分的简单分类，而是强烈关注于阐明特定核糖体蛋白、其同源异构体和共价修饰的功能。本文总结了目前关于拟南芥细胞质核糖体蛋白组的知识，并强调了在这个快速发展和重要领域中未来研究的潜在有成果的方向。
