Department of Family Medicine, Oregon Health & Science University, Portland, OR;
Nicotine Tob Res. 2013 Oct;15(10):1655-62. doi: 10.1093/ntr/ntt017. Epub 2013 Mar 4.
Relatively few well-designed smoking cessation studies have been conducted with teen smokers. This study examined the efficacy of extended cognitive-behavioral treatment in promoting longer term smoking cessation among adolescents.
Open-label smoking cessation treatment consisted of 10 weeks of school-based, cognitive-behavioral group counseling along with 9 weeks of nicotine replacement (nicotine patch). A total of 141 adolescent smokers in continuation high schools in the San Francisco Bay Area were randomized to either 9 additional group sessions over a 14-week period (extended group) or 4 monthly smoking status calls (nonextended group). Intention-to-treat logistic regression analysis was used to assess the primary outcome of biologically confirmed (carbon monoxide < 9 ppm) point prevalence abstinence at Week 26 (6-month follow-up from baseline).
At Week 26 follow-up, the extended treatment group had a significantly higher abstinence rate (21%) than the nonextended treatment (7%; OR = 4.24, 95% CI: 1.20-15.02). Females also were more likely to be abstinent at the follow-up than males (OR = 4.15, 95% CI: 1.17-14.71).
The significantly higher abstinence rate at follow-up for the extended treatment group provides strong support for continued development of longer term interventions for adolescent smoking cessation.
很少有精心设计的戒烟研究针对青少年吸烟者进行。本研究旨在检验延长认知行为治疗对促进青少年长期戒烟的疗效。
开放性戒烟治疗包括 10 周的学校认知行为小组辅导，以及 9 周的尼古丁替代（尼古丁贴片）治疗。旧金山湾区继续高中的 141 名青少年吸烟者被随机分配到为期 14 周的 9 次额外小组会议（延长组）或 4 次每月吸烟状况电话随访（非延长组）。采用意向治疗逻辑回归分析评估主要结局：第 26 周（从基线开始的 6 个月随访）通过生物确认（一氧化碳<9ppm）的点患病率戒烟。
在第 26 周随访时，延长治疗组的戒烟率（21%）明显高于非延长治疗组（7%；OR=4.24，95%CI：1.20-15.02）。女性的戒烟率也明显高于男性（OR=4.15，95%CI：1.17-14.71）。
延长治疗组在随访时的戒烟率明显较高，为青少年戒烟的长期干预措施的进一步发展提供了有力支持。
