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立陶宛 2 型糖尿病患者的生活质量与社会和疾病因素的关系。

Quality of life in relation to social and disease factors in patients with type 2 diabetes in Lithuania.

机构信息

Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

出版信息

Med Sci Monit. 2013 Mar 6;19:165-74. doi: 10.12659/MSM.883823.

Abstract

BACKGROUND

Diabetic patients are more than twice as costly to manage as non-diabetic patients, due mainly to the high costs associated with management of diabetic complications. As in most nations of the world, the number of patients with DM is increasing every year in Lithuania. The aim of this study was to determine relation between quality of the life and disease and social factors of patients with type 2 diabetes in Lithuania.

MATERIAL AND METHODS

Independently prepared questions about the subjects of the survey were: gender; age; weight; education; social and marital status; duration of the disease (in years); treatment method; complications; morbidity with arterial hypertension; change in dietary habits after diagnosis of diabetes (started to eat accordingly to recommendations of the therapist); how often nourishment is taken accordingly to recommendations of the therapist; if beginning to exercise after diagnosis of the diabetes; and if exercising, exercises at least 2-3 times per week. Body mass index was calculated as the relation between body mass in kg and height m square (BMI=kg/m2). The hospital anxiety and depression (HAD) scale was used for the evaluation of depression and anxiety. Quality of life of patients was evaluated with the SF-36 questionnaire. We surveyed 1022 patients with type 2 diabetes (372 men and 650 women). Association between quality of the life and explanatory parameters (disease and social factors) were analyzed using the logistic regression analysis model.

RESULTS

We found that women had lower scores than men in all fields of quality of life (p<0.001). Peroral treatment had a positive impact on the quality of life (QL) fields of the role limitations due to emotional problems (ORa 0.16. 95% CI 0.07-0.34; p<0.001). Treatment with insulin had a positive effect on restriction of activity because of emotional problems (ORa - 0.23. 95% CI 0.11-0.49; p<0.001) and mental health (ORa - 0.38. 95% CI 0.19-0.78; p=0.008), but had a negative impact on bodily pain (ORa - 3.95. 95% CI 1.41-11.09; p=0.009) and physical health (ORa - 4.14. 95% CI 2.03-8.47; p<0.001).

CONCLUSIONS

Age and BMI are less important factors that can influence quality of life. Peroral treatment positively acted on the role limitations due to emotional problems, bodily pain, and mental health, but had a strong negative effect on emotional state.

摘要

背景

糖尿病患者的管理成本是非糖尿病患者的两倍以上,主要是由于与糖尿病并发症管理相关的高成本。与世界上大多数国家一样,立陶宛的糖尿病患者数量每年都在增加。本研究的目的是确定立陶宛 2 型糖尿病患者的生活质量与疾病和社会因素之间的关系。

材料和方法

独立准备的关于调查主题的问题包括:性别;年龄;体重;教育程度;社会和婚姻状况;疾病持续时间(年);治疗方法;并发症;动脉高血压发病率;糖尿病诊断后饮食习惯的改变(开始按照治疗师的建议进食);根据治疗师的建议,进食的频率;糖尿病诊断后是否开始运动;如果运动,每周至少运动 2-3 次。体重指数是体重(kg)与身高(m)平方的比值(BMI=kg/m2)。采用医院焦虑抑郁量表(HAD)评估抑郁和焦虑。使用 SF-36 问卷评估患者的生活质量。我们调查了 1022 名 2 型糖尿病患者(372 名男性和 650 名女性)。使用逻辑回归分析模型分析生活质量与解释性参数(疾病和社会因素)之间的关系。

结果

我们发现,女性在生活质量的所有领域的得分均低于男性(p<0.001)。口服治疗对情绪问题导致的角色限制(ORa 0.16,95%CI 0.07-0.34;p<0.001)领域的生活质量有积极影响。胰岛素治疗对情绪问题导致的活动受限(ORa -0.23,95%CI 0.11-0.49;p<0.001)和心理健康(ORa -0.38,95%CI 0.19-0.78;p=0.008)有积极影响,但对身体疼痛(ORa -3.95,95%CI 1.41-11.09;p=0.009)和身体健康(ORa -4.14,95%CI 2.03-8.47;p<0.001)有负面影响。

结论

年龄和 BMI 是影响生活质量的不太重要的因素。口服治疗对情绪问题导致的角色限制、身体疼痛和心理健康有积极作用,但对情绪状态有强烈的负面影响。

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