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单次 session 的经内镜逆行胰胆管造影术和内镜超声检查术用于胆胰疾病是可行的、有效的,并且具有成本效益。

Single-session endosonography and endoscopic retrograde cholangiopancreatography for biliopancreatic diseases is feasible, effective and cost beneficial.

机构信息

Department of Digestive Diseases, Hospital Universitari de Bellvitge-IDIBELL, L'Hospitalet de Llobregat, Barcelona, Catalonia, Spain.

出版信息

Dig Liver Dis. 2013 Jul;45(7):578-83. doi: 10.1016/j.dld.2013.01.023. Epub 2013 Mar 5.

Abstract

BACKGROUND

Endoscopic ultrasonography (EUS) and Endoscopic Retrograde Cholangiopancreatography (ERCP) are often required in patients with pancreaticobiliary disorders.

AIMS

To assess the clinical impact and costs savings of a single session EUS-ERCP.

METHODS

Patient and intervention data from April 2009 to March 2012 were prospectively recruited and retrospectively analyzed from a database at a tertiary hospital. Indications, diagnostic yield, procedure details, complications and costs were evaluated.

RESULTS

Fifty-five scheduled combined procedures were done in 53 patients. The accuracy of EUS-fine needle aspiration for malignancy was 90%. The main clinical indication was a malignant obstructing lesion (66%). The ERCP cannulation was successful in 67%, and in 11/15 failed ERCP (73%), drainage was completed thanks to an EUS-guided biliary drainage: 6 transmurals, 5 rendezvous. Eight patients (14%) had related complications: bacteremia (n = 3), pancreatitis (n = 2), bleeding (n = 2) and perforation (n = 1). The mean duration was 65 ± 22.2 min. The mean estimated cost for a single session was €3437, and €4095 for two separate sessions. The estimated cost savings using a single-session strategy was €658 per patient, representing a total savings of €36,189.

CONCLUSION

Combined EUS and ERCP is safe, technically feasible and cost beneficial. Furthermore, in failed ERCP cases, the endoscopic biliary drainage can be completed with EUS-guided biliary access in the same procedure.

摘要

背景

在胰胆疾病患者中,通常需要进行内镜超声检查(EUS)和内镜逆行胰胆管造影术(ERCP)。

目的

评估单次 EUS-ERCP 的临床影响和成本节约。

方法

从一家三级医院的数据库中前瞻性招募并回顾性分析 2009 年 4 月至 2012 年 3 月期间的患者和干预数据。评估了适应证、诊断率、操作细节、并发症和成本。

结果

53 例患者进行了 55 例计划联合手术。EUS 细针抽吸对恶性肿瘤的准确率为 90%。主要的临床适应证是恶性阻塞性病变(66%)。ERCP 插管成功率为 67%,在 15 例失败的 ERCP 中(73%),由于 EUS 引导的胆道引流完成了引流:6 例经壁,5 例会师。8 例患者(14%)出现相关并发症:菌血症(n=3)、胰腺炎(n=2)、出血(n=2)和穿孔(n=1)。平均手术时间为 65±22.2 分钟。单次治疗的平均估计费用为 3437 欧元,两次单独治疗的费用为 4095 欧元。单次治疗策略的估计成本节约为每位患者 658 欧元,总节约额为 36189 欧元。

结论

联合 EUS 和 ERCP 是安全的,技术上可行且具有成本效益。此外,在 ERCP 失败的情况下,可以通过 EUS 引导的胆道进入在同一手术中完成胆道引流。

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