Department of Digestive Diseases, Hospital Universitari de Bellvitge-IDIBELL, L'Hospitalet de Llobregat, Barcelona, Catalonia, Spain.
Dig Liver Dis. 2013 Jul;45(7):578-83. doi: 10.1016/j.dld.2013.01.023. Epub 2013 Mar 5.
Endoscopic ultrasonography (EUS) and Endoscopic Retrograde Cholangiopancreatography (ERCP) are often required in patients with pancreaticobiliary disorders.
To assess the clinical impact and costs savings of a single session EUS-ERCP.
Patient and intervention data from April 2009 to March 2012 were prospectively recruited and retrospectively analyzed from a database at a tertiary hospital. Indications, diagnostic yield, procedure details, complications and costs were evaluated.
Fifty-five scheduled combined procedures were done in 53 patients. The accuracy of EUS-fine needle aspiration for malignancy was 90%. The main clinical indication was a malignant obstructing lesion (66%). The ERCP cannulation was successful in 67%, and in 11/15 failed ERCP (73%), drainage was completed thanks to an EUS-guided biliary drainage: 6 transmurals, 5 rendezvous. Eight patients (14%) had related complications: bacteremia (n = 3), pancreatitis (n = 2), bleeding (n = 2) and perforation (n = 1). The mean duration was 65 ± 22.2 min. The mean estimated cost for a single session was €3437, and €4095 for two separate sessions. The estimated cost savings using a single-session strategy was €658 per patient, representing a total savings of €36,189.
Combined EUS and ERCP is safe, technically feasible and cost beneficial. Furthermore, in failed ERCP cases, the endoscopic biliary drainage can be completed with EUS-guided biliary access in the same procedure.
在胰胆疾病患者中,通常需要进行内镜超声检查(EUS)和内镜逆行胰胆管造影术(ERCP)。
评估单次 EUS-ERCP 的临床影响和成本节约。
从一家三级医院的数据库中前瞻性招募并回顾性分析 2009 年 4 月至 2012 年 3 月期间的患者和干预数据。评估了适应证、诊断率、操作细节、并发症和成本。
53 例患者进行了 55 例计划联合手术。EUS 细针抽吸对恶性肿瘤的准确率为 90%。主要的临床适应证是恶性阻塞性病变(66%)。ERCP 插管成功率为 67%,在 15 例失败的 ERCP 中(73%),由于 EUS 引导的胆道引流完成了引流:6 例经壁,5 例会师。8 例患者(14%)出现相关并发症:菌血症(n=3)、胰腺炎(n=2)、出血(n=2)和穿孔(n=1)。平均手术时间为 65±22.2 分钟。单次治疗的平均估计费用为 3437 欧元,两次单独治疗的费用为 4095 欧元。单次治疗策略的估计成本节约为每位患者 658 欧元,总节约额为 36189 欧元。
联合 EUS 和 ERCP 是安全的,技术上可行且具有成本效益。此外,在 ERCP 失败的情况下,可以通过 EUS 引导的胆道进入在同一手术中完成胆道引流。