Kemmett D, Ellis J, Spencer M J, Hunter J A
University Department of Dermatology, Royal Infirmary, Edinburgh, UK.
Clin Exp Dermatol. 1990 Mar;15(2):111-4. doi: 10.1111/j.1365-2230.1990.tb02044.x.
The Laugier-Hunziker syndrome is an acquired, benign, macular hyperpigmentation of the lips and buccal mucosa. The nails are often involved with the development of melanonychia. Twenty-two previous cases have been recorded in the literature. We present details of six Caucasian patients with the Laugier-Hunziker syndrome who are the first recorded from Britain. They all had acquired, macular hyperpigmentation of the lips and buccal mucosa. In five of these patients longitudinal pigmented bands were found on the nails. None had other family members affected. Although this is the first report of British patients with this syndrome, we believe that the condition is probably more common than is generally recognized.
劳吉尔-杭齐克尔综合征是一种后天获得性的、良性的唇部和颊黏膜黄斑色素沉着症。指甲常伴有甲下黑素沉着。此前文献已记载22例病例。我们介绍6例患有劳吉尔-杭齐克尔综合征的白种人患者的详细情况,这是英国首次记录的此类病例。他们均有后天获得性的唇部和颊黏膜黄斑色素沉着。其中5例患者指甲出现纵向色素带。均无其他家庭成员患病。尽管这是英国患者患此综合征的首例报告,但我们认为该病可能比普遍认知的更为常见。