Rangwala Sophia, Doherty Christy B, Katta Rajani
Department of Dermatology, Baylor College of Medicine, Houston, Texas, USA.
Dermatol Online J. 2010 Dec 15;16(12):9.
Laugier-Hunziker syndrome (LHS) is a rare acquired disorder characterized by diffuse macular hyperpigmentation of the oral mucosa and, at times, longitudinal melanonychia. Although LHS is considered a benign disease with no systemic manifestations or malignant potential, it is important to rule out other mucocutaneous pigmentary disorders that do require medical management. Prompt clinical recognition also averts the need for excessive and invasive procedures and treatments. To date, only four cases have been reported in the United States. We present a 77-year-old man who had clinical features typical of LHS and we then provide a review of the literature on LHS and its mimickers.
劳吉尔-杭齐克尔综合征(LHS)是一种罕见的后天性疾病,其特征为口腔黏膜弥漫性黄斑色素沉着,有时还伴有甲纵嵴黑甲。尽管LHS被认为是一种无全身表现或恶性潜能的良性疾病,但排除其他确实需要医学处理的黏膜皮肤色素沉着障碍很重要。及时的临床识别还可避免过度和侵入性的检查及治疗。迄今为止,美国仅报告了4例病例。我们报告一名具有LHS典型临床特征的77岁男性,然后对LHS及其模仿者的文献进行综述。