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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Bachmann A W, Gordon R D, Bathgate R A, Thompson R E

University of Queensland, Department of Medicine, Greenslopes Hospital, Brisbane, Australia.

Clin Exp Pharmacol Physiol. 1990 Apr;17(4):257-61. doi: 10.1111/j.1440-1681.1990.tb01317.x.

Arterial adrenaline (ADR) levels were measured during graded ADR infusions in normotensives (NT) and in mild hypertensives (HT), in order to test the hypothesis that ADR enhances its own clearance in NT. 2. Although infusion of ADR resulted in similar arterial ADR levels in NT and HT, increases in systolic blood pressure (SBP) and heart rate (HR) and decreases in diastolic blood pressure (DBP) were greater during ADR infusion in HT than in NT. 3. Twenty minutes after cessation of infusion, SBP and HR remained elevated in HT but not in NT. 4. No evidence was found supporting enhanced ADR clearance during increasing ADR levels in NT or HT.

在正常血压者（NT）和轻度高血压患者（HT）中进行分级输注肾上腺素（ADR）时测量动脉血ADR水平，以检验ADR增强其在NT中自身清除率的假说。2. 尽管在NT和HT中输注ADR导致相似的动脉血ADR水平，但在HT中输注ADR期间收缩压（SBP）和心率（HR）的升高以及舒张压（DBP）的降低比在NT中更大。3. 输注停止20分钟后，HT中的SBP和HR仍升高，而NT中则不然。4. 未发现证据支持在NT或HT中ADR水平升高期间ADR清除率增强。

Bachmann A W, Gordon R D, Bathgate R A, Thompson R E

University of Queensland, Department of Medicine, Greenslopes Hospital, Brisbane, Australia.

Clin Exp Pharmacol Physiol. 1990 Apr;17(4):257-61. doi: 10.1111/j.1440-1681.1990.tb01317.x.

Arterial adrenaline (ADR) levels were measured during graded ADR infusions in normotensives (NT) and in mild hypertensives (HT), in order to test the hypothesis that ADR enhances its own clearance in NT. 2. Although infusion of ADR resulted in similar arterial ADR levels in NT and HT, increases in systolic blood pressure (SBP) and heart rate (HR) and decreases in diastolic blood pressure (DBP) were greater during ADR infusion in HT than in NT. 3. Twenty minutes after cessation of infusion, SBP and HR remained elevated in HT but not in NT. 4. No evidence was found supporting enhanced ADR clearance during increasing ADR levels in NT or HT.

在正常血压者（NT）和轻度高血压患者（HT）中进行分级输注肾上腺素（ADR）时测量动脉血ADR水平，以检验ADR增强其在NT中自身清除率的假说。2. 尽管在NT和HT中输注ADR导致相似的动脉血ADR水平，但在HT中输注ADR期间收缩压（SBP）和心率（HR）的升高以及舒张压（DBP）的降低比在NT中更大。3. 输注停止20分钟后，HT中的SBP和HR仍升高，而NT中则不然。4. 未发现证据支持在NT或HT中ADR水平升高期间ADR清除率增强。