澳大利亚和新西兰完整健康改善计划（CHIP）在降低特定慢性病风险因素方面的有效性：一项可行性研究。

The effectiveness of the Complete Health Improvement Program (CHIP) in Australasia for reducing selected chronic disease risk factors: a feasibility study.

作者信息

Morton Darren P, Rankin Paul, Morey Peter, Kent Lillian, Hurlow Trevor, Chang Esther, Diehl Hans

机构信息

Lifestyle Education Research Group, Faculty of Education and Science, Avondale College of Higher Education, Cooranbong, NSW 2265, Australia.

出版信息

N Z Med J. 2013 Mar 1;126(1370):43-54.

PMID:23474512

Abstract

AIM

To examine the effectiveness within the Australasian context of the Complete Health Improvement Program (CHIP) lifestyle intervention, which has been shown to produce meaningful reductions in selected chronic disease risk factors in the United States.

METHODS

Changes in body weight, blood pressure, blood lipid profile and fasting plasma glucose were assessed in 836 self-selected participants (age=55.9 plus or minus 12.7 yrs, 35% male/65% female) from 18 sites throughout New Zealand (N=731) and Australia (N=105).

RESULTS

In the 30 days of the program, significant overall reductions (p<0.001) were recorded in the participants' body mass (-3.8%; 87.1 plus or minus 22.4 versus 83.9 plus or minus 21.5 kg), systolic blood pressure (-5.6%; 135 plus or minus 19 versus 127 plus or minus 17 mmHg), diastolic blood pressure (-4.6%; 80 plus or minus 12 versus 76 plus or minus 12 mmHg), total cholesterol (-14.7%; 5.17 plus or minus 1.08 versus 4.41 plus or minus 0.96 mmol/L), low-density lipoprotein cholesterol (-17.9%; 3.17 plus or minus 0.95 versus 2.60 plus or minus 0.83 mmol/L), triglycerides (-12.5%; 1.51 plus or minus 0.98 versus 1.32 plus or minus 0.71 mmol/L) and fasting plasma glucose (-5.6%; 5.55 plus or minus 1.49 versus 5.24 plus or minus 1.11 mmol/L). Participants at program entry with the highest classifications of total cholesterol, low-density lipoprotein, triglycerides and fasting plasma glucose experienced over 20% reductions in these measures in 30 days.

CONCLUSIONS

Significant reductions in selected chronic disease risk factors were observed in 30 days using the CHIP intervention and the improvements were comparable to that observed in cohorts from the United States. The results of this feasibility study indicate that lifestyle interventions like CHIP may be useful for combating the burgeoning epidemic of chronic disease and further research is warranted.

摘要

目的

研究全面健康改善计划（CHIP）生活方式干预措施在澳大拉西亚地区的效果，该干预措施在美国已被证明能显著降低某些慢性病风险因素。

方法

对来自新西兰（n = 731）和澳大利亚（n = 105）18个地点的836名自行选择的参与者（年龄 = 55.9±12.7岁，男性占35%/女性占65%）的体重、血压、血脂谱和空腹血糖变化进行评估。

结果

在该计划的30天内，参与者的体重（-3.8%；87.1±22.4 vs 83.9±21.5千克）、收缩压（-5.6%；135±19 vs 127±17毫米汞柱）、舒张压（-4.6%；80±12 vs 76±12毫米汞柱）、总胆固醇（-14.7%；5.17±1.08 vs 4.41±0.96毫摩尔/升）、低密度脂蛋白胆固醇（-17.9%；3.17±0.95 vs 2.60±0.83毫摩尔/升）、甘油三酯（-12.5%；1.51±0.98 vs 1.32±0.71毫摩尔/升）和空腹血糖（-5.6%；5.55±1.49 vs 5.24±1.11毫摩尔/升）均有显著的总体下降（p < 0.001）。在项目开始时总胆固醇、低密度脂蛋白、甘油三酯和空腹血糖分类最高的参与者，这些指标在30天内下降超过20%。