Department of Geriatric Medicine/Gerontology, Ohio University Heritage College of Osteopathic Medicine, Athens, OH, USA,
AIDS Behav. 2013 Nov;17(9):3034-44. doi: 10.1007/s10461-013-0441-0.
This clinical trial tested whether telephone-administered supportive-expressive group therapy or coping effectiveness training reduce depressive symptoms in HIV-infected older adults. Participants from 24 states (N = 361) completed the Geriatric Depression Scale at pre-intervention, post-intervention, and 4- and 8-month follow-up and were randomized to one of three study arms: (1) 12 weekly sessions of telephone-administered, supportive-expressive group therapy (tele-SEGT; n = 122); (2) 12 weekly sessions of telephone-administered, coping effectiveness training (tele-CET; n = 118); or (3) a standard of care (SOC) control group (n = 121). Tele-SEGT participants reported fewer depressive symptoms than SOC controls at post-intervention (MSEGT = 11.9, MSOC = 14.3) and 4- (MSEGT = 12.5, MSOC = 14.4) and 8-month follow-up (MSEGT = 12.7, MSOC = 14.5) and fewer depressive symptoms than tele-CET participants at post-intervention (MSEGT = 12.4, MCET = 13.6) and 8-month follow-up (MSEGT = 12.7, MCET = 14.1). Tele-CET participants reported no statistically significant differences from SOC controls in GDS values at any assessment period. Tele-SEGT constitutes an efficacious treatment to reduce depressive symptoms in HIV-infected older adults.
这项临床试验旨在测试电话辅助支持表达团体治疗或应对效能训练是否能降低感染 HIV 的老年患者的抑郁症状。来自 24 个州的参与者(N = 361)在干预前、干预后以及 4 个月和 8 个月的随访中完成了老年抑郁量表(Geriatric Depression Scale),并被随机分配到三个研究组之一:(1)12 周的电话辅助支持表达团体治疗(tele-SEGT;n = 122);(2)12 周的电话辅助应对效能训练(tele-CET;n = 118);或(3)标准护理(SOC)对照组(n = 121)。与 SOC 对照组相比,在干预后(MSEGT = 11.9,MSOC = 14.3)和 4 个月(MSEGT = 12.5,MSOC = 14.4)和 8 个月随访时(MSEGT = 12.7,MSOC = 14.5),接受 tele-SEGT 的参与者报告的抑郁症状更少,而与接受 tele-CET 的参与者相比,在干预后(MSEGT = 12.4,MCET = 13.6)和 8 个月随访时(MSEGT = 12.7,MCET = 14.1),报告的抑郁症状也更少。接受 tele-CET 的参与者在任何评估期间与 SOC 对照组在 GDS 值上均无统计学显著差异。Tele-SEGT 是一种有效的治疗方法,可降低感染 HIV 的老年患者的抑郁症状。