Messina Diego, Pérez Elizalde Rafael, Soto Catalina, Uvilla Ana, López Laur José Daniel, López Fontana Constanza
Laboratorio de Enfermedades Metabólicas y Cáncer, Facultad de Farmacia y Bioquímica, Universidad Juan Agustín Maza.
Arch Latinoam Nutr. 2012 Mar;62(1):15-22.
The body's antioxidant systems are able to remove free radicals, thus protecting the body from the damage they may cause. They can be estimated, as a whole, through the determination of total antioxidant status (TAS). This biomarker can be modulated by dietary factors through the incorporation of substances with antioxidant or prooxidant properties. The aim of this study was to estimate the intake of antioxidant nutrients and specific food groups, and its correlation with TAS. Forty-five male volunteers between 50 and 75 years were randomly selected from a medical consultation. The study included a TAS determination by ABTS and a nutritional interview where corporal composition was studied through anthropometry and the habitual consumption of nutrients was estimated by means of 24 hour diary and food consumption frequency questionnaire. Statistical analysis was performed by using Pearson or Spearman correlation coefficient (p < 0.05). TAS was positively correlated with lycopene consumption (r = 0.295; p = 0.049), and negatively with red meat intake (r = -0.403; p = 0.007), while intake of other studied antioxidant nutrients did not correlate significantly with TAS. In conclusion, high intake of lycopene and reduced red meat consumption increase TAS.
人体的抗氧化系统能够清除自由基,从而保护身体免受自由基可能造成的损害。总体而言,可通过测定总抗氧化状态(TAS)来评估这些系统。这种生物标志物可通过摄入具有抗氧化或促氧化特性的物质,受饮食因素的调节。本研究的目的是评估抗氧化营养素和特定食物组的摄入量及其与TAS的相关性。从一次医疗咨询中随机选取了45名年龄在50至75岁之间的男性志愿者。该研究包括通过ABTS法测定TAS以及进行营养访谈,其中通过人体测量学研究身体成分,并通过24小时饮食日记和食物消费频率问卷评估营养素的习惯性摄入量。使用Pearson或Spearman相关系数进行统计分析(p < 0.05)。TAS与番茄红素摄入量呈正相关(r = 0.295;p = 0.049),与红肉摄入量呈负相关(r = -0.403;p = 0.007),而其他研究的抗氧化营养素摄入量与TAS无显著相关性。总之,高番茄红素摄入量和减少红肉消费可提高TAS。