Marques Anne Y Castro, Dragano Nathalia Romanelli, Lenquiste Sabrina Alves, Batista Angela Giovana, Palazzo Carina Carlucci, Maróstica Mário Roberto
Department of Food and Nutrition, Faculty of Food Engineering, University of Campinas, Campinas, São Paulo State, Brazil.
Arch Latinoam Nutr. 2012 Mar;62(1):37-43.
Jaboticaba, a native fruit from Brazilian Atlantic Forest, is an important source of anthocyanins. Anthocyanins have been recently identified as modulators of lipid metabolism and energy expenditure 'in vivo'. The purpose of this study was to evaluate the effect of the freeze-dried jaboticaba peel powder on obesity treatment in different experimental models. Obese Swiss mice and obese Sprague-Dawley rats were fed a high-fat diet supplemented with 1, 2 and 4% freeze-dried jaboticaba peel powder for 6 weeks. Energy intake, weight gain and body composition were determined, and the results were analyzed using variance and Tukey's tests (p < 0.05). The energy intake was higher in mice groups supplemented with 2% and 4% of jaboticaba peel. In relation to weight gain, the mice supplemented with 2% of jaboticaba peel had higher total weight gain than the other experimental groups, while no significant difference in the fat mass accumulation was observed among the groups. The rats did not show significant differences in the evaluated parameters. These results suggest that the supplementation with freeze-dried jaboticaba peel powder, at concentrations of 1, 2 and 4%, was not effective in the reduction of energy intake, weight gain and body fat both in mice and in rats.
嘉宝果是一种原产于巴西大西洋森林的水果，是花青素的重要来源。花青素最近被确定为体内脂质代谢和能量消耗的调节剂。本研究的目的是评估冻干嘉宝果皮粉在不同实验模型中对肥胖治疗的效果。将肥胖的瑞士小鼠和肥胖的斯普拉格-道利大鼠喂食添加了1%、2%和4%冻干嘉宝果皮粉的高脂饮食6周。测定能量摄入、体重增加和身体组成，并使用方差分析和Tukey检验分析结果（p<0.05）。添加2%和4%嘉宝果皮的小鼠组能量摄入较高。关于体重增加，添加2%嘉宝果皮的小鼠总体重增加高于其他实验组，而各组之间脂肪量积累未观察到显著差异。大鼠在评估参数上未显示出显著差异。这些结果表明，添加1%、2%和4%浓度的冻干嘉宝果皮粉对降低小鼠和大鼠的能量摄入、体重增加和体脂均无效。
