Peragallo Jason H, Velez Federico G, Demer Joseph L, Pineles Stacy L
Jules Stein Eye Institute and Department of Ophthalmology, University of California, Los Angeles, California, USA.
Strabismus. 2013 Mar;21(1):23-8. doi: 10.3109/09273972.2012.762533.
Extraocular muscles of patients with thyroid ophthalmopathy (TO) may respond differently to strabismus surgery than those of other strabismic patients. This study reports postoperative alignment changes in patients with TO compared with patients with non-restrictive strabismus following unilateral inferior rectus muscle recession (IRR).
We reviewed records of patients with and without TO who underwent unilateral IRR. Group A had adjustable muscle sutures, while Group B had permanent or semi-adjustable sutures. Controls were patients undergoing adjustable unilateral IRR for other indications.
Mean preoperative hypotropias were 17 ± 9, 21 ± 7, and 11 ± 4 PD for groups A (n=13), B (n=14), and controls (n=19), respectively. Postoperative day one (POD1) measurements after adjustment were 1.2 ± 2.5, 3.7 ± 4.9, and 0.3 ± 2.4 PD, respectively, representing overall undercorrections in all cases (the preoperative deviation was given a positive (+) value and overcorrections were deemed negative (-) deviations). Dose response from linear regression analysis of thyroid patients compared with control patients for IRR was 3.26 PD/mm (SE 0.18) vs 2.38 PD/mm (SE 0.18) (p=0.001). Mean final measurements were -0.7 ± 5.6 (overcorrection), 2.7 ± 5.7, and 1.7 ± 5.7 PD of hypotropia, respectively. Final overcorrections occurred in 23%, 14%, and 16% of patients, for adjustables, permanent sutures, and control subjects, respectively. Drifts from POD1 measurements after adjustment to final measurements were -1.9 ± 4.3, -1.0 ± 4.6, and 1.4 ± 5.9 PD respectively (p=0.05 for comparison between Group A and controls).
TO patients with adjustable sutures drift toward postoperative overcorrection.
甲状腺眼病(TO)患者的眼外肌对斜视手术的反应可能与其他斜视患者不同。本研究报告了与非限制性斜视患者相比,TO患者在单侧下直肌后徙术(IRR)后的术后眼位矫正变化。
我们回顾了接受单侧IRR的TO患者和非TO患者的记录。A组采用可调节肌肉缝线,而B组采用永久性或半可调节缝线。对照组为因其他适应症接受可调节单侧IRR的患者。
A组(n = 13)、B组(n = 14)和对照组(n = 19)术前平均下斜视度数分别为17±9、21±7和11±4棱镜度(PD)。调整后术后第1天(POD1)的测量值分别为1.2±2.5、3.7±4.9和0.3±2.4 PD,表明所有病例均存在总体矫正不足(术前偏差给予正值(+),过矫正视为负值(-)偏差)。甲状腺患者与对照组患者IRR的线性回归分析剂量反应分别为3.26 PD/mm(标准误0.18)和2.38 PD/mm(标准误0.18)(p = 0.001)。最终平均测量值分别为-0.7±5.6(过矫正)、2.7±5.7和1.7±5.7 PD的下斜视。可调节缝线组、永久性缝线组和对照组患者最终过矫正的发生率分别为23%、14%和16%。从调整后的POD1测量值到最终测量值的漂移分别为-1.9±-4.3、-1.0±4.6和1.4±5.9 PD(A组与对照组比较,p = 0.05)。
采用可调节缝线的TO患者术后倾向于过矫正。