Esfahan University of Medical Sciences, Esfahan, Iran; Beheshti Hospital, Motahari Street, Esfahan, Iran.
Placenta. 2013 May;34(5):460-2. doi: 10.1016/j.placenta.2013.01.010. Epub 2013 Mar 9.
Placental site trophoblastic tumor (PSTT) is the rarest type of gestational trophoblastic tumors. Common presentation is irregular vaginal bleeding. A 26-year-old G1P1 woman presented with 15 month amenorrhea, a large uterine mass and plateau low level of serum human chorionic gonadotropin (hCG) which raised the possibility of PSTT. Since whole myometrium had been substituted with the large tumoral mass, hysterectomy was considered despite the young age of the patient. The patient has been in remission 36 months postoperatively without receiving any adjuvant treatment. It seems that plateau low levels of hCG in the presence of amenorrhea should prompt the possibility of PSTT.
胎盘部位滋养细胞肿瘤(PSTT)是最罕见的妊娠滋养细胞肿瘤类型。常见表现为不规则阴道出血。一位 26 岁 G1P1 的女性因 15 个月闭经、子宫巨大肿块和血清人绒毛膜促性腺激素(hCG)水平低而就诊,hCG 水平低提示可能患有 PSTT。由于整个子宫肌层已被巨大的肿瘤肿块所取代,尽管患者年龄较轻,但仍考虑行子宫切除术。术后 36 个月患者无疾病复发且未接受任何辅助治疗。对于闭经且 hCG 水平低的患者,应警惕 PSTT 的可能。