DeLellis Stephen M, Anderson Steven E, Lynch James H, Kratz Kris
Department of the Army, Womack Army Medical Center, Womack Family Medicine Clinic, Fort Bragg, NC 28310, USA.
Curr Sports Med Rep. 2013 Mar-Apr;12(2):110-4. doi: 10.1249/JSR.0b013e3182874d0f.
Acute mountain sickness (AMS) is the most common form of altitude illness affecting athletes and adventurists who work or play at elevations greater than 10,000 ft above mean sea level. Considerable research has been conducted to mitigate risk for those who work or play in environmental extremes. This article describes the experiences of a group of U.S. Army Special Operations soldiers who tested recommended doses of acetazolamide prophylaxis for AMS during six expeditions to elevations between 19,000 and 23,000 ft. In addition, we briefly review the literature as it pertains to prophylaxis of AMS. In our experience, prophylaxis with the recommended doses of acetazolamide resulted in fewer AMS symptoms and seemed to confer a higher likelihood of successfully summiting each peak. We conclude that acetazolamide is an acceptable choice for AMS prevention along with a slow, controlled ascent and proper fitness, nutrition, clothing, and gear.
急性高原病（AMS）是海拔病最常见的形式，影响在平均海平面10000英尺以上工作或运动的运动员和冒险家。针对那些在极端环境中工作或运动的人群，已经开展了大量研究以降低风险。本文描述了一组美国陆军特种部队士兵的经历，他们在6次海拔19000至23000英尺的探险中测试了预防急性高原病的推荐剂量的乙酰唑胺。此外，我们简要回顾了与急性高原病预防相关的文献。根据我们的经验，使用推荐剂量的乙酰唑胺进行预防可减少急性高原病症状，并且似乎增加了成功登顶每座山峰的可能性。我们得出结论，乙酰唑胺是预防急性高原病的一个可接受的选择，同时还需要缓慢、有控制的上升以及适当的体能、营养、衣物和装备。
