INRS institut Armand-Frappier, 531 Boulevard des Prairies, Laval, Quebec, Canada, H7V 1B7.
Philos Trans R Soc Lond B Biol Sci. 2013 Mar 11;368(1616):20120319. doi: 10.1098/rstb.2012.0319. Print 2013 Apr 19.
In this report, a complete description of Desulfitobacterium hafniense strain PCP-1 is presented. The D. hafniense strain PCP-1 was isolated from a methanogenic consortium for its capacity to dehalogenate pentachlorophenol (PCP) into 3-chlorophenol. This strain is also capable of dehalogenating several other chloroaromatic compounds and tetrachloroethene into trichloroethene. Four gene loci encoding putative chlorophenol-reductive dehalogenases (CprA2 to CprA5) were detected, and the products of two of these loci have been demonstrated to dechlorinate different chlorinated phenols. Strain PCP-1 was used in laboratory-scale bioprocesses to degrade PCP present in contaminated environments. Desulfitobacterium hafniense PCP-1 is an excellent candidate for the development of efficient bioprocesses to degrade organohalide compounds.
本报告全面描述了脱硫反硝化杆菌(Desulfitobacterium hafniense)菌株 PCP-1。该菌株是从一个产甲烷菌共生物种中分离出来的,因其能够将五氯酚(PCP)脱卤化为 3-氯苯酚而被选中。该菌株还能够将其他几种氯代芳烃化合物和四氯乙烯脱卤化为三氯乙烯。检测到四个编码潜在的氯酚还原脱卤酶(CprA2 至 CprA5)的基因座,其中两个基因座的产物已被证明能够脱除不同的氯代酚。在实验室规模的生物工艺中,使用菌株 PCP-1 降解污染环境中存在的五氯酚。脱硫反硝化杆菌 PCP-1 是开发高效生物工艺降解有机卤化物化合物的理想候选菌株。