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本文引用的文献

1
Why are chlorinated pollutants so difficult to degrade aerobically? Redox stress limits 1,3-dichloroprop-1-ene metabolism by Pseudomonas pavonaceae.为什么氯化污染物如此难以在有氧条件下降解?氧化还原应激限制了假单胞菌属对 1,3-二氯-1-丙烯的代谢。
Philos Trans R Soc Lond B Biol Sci. 2013 Mar 11;368(1616):20120377. doi: 10.1098/rstb.2012.0377. Print 2013 Apr 19.
2
Identification of a reductive tetrachloroethene dehalogenase in Shewanella sediminis.希瓦氏菌中还原型四氯乙烯脱卤酶的鉴定。
Philos Trans R Soc Lond B Biol Sci. 2013 Mar 11;368(1616):20120326. doi: 10.1098/rstb.2012.0326. Print 2013 Apr 19.
3
The restricted metabolism of the obligate organohalide respiring bacterium Dehalobacter restrictus: lessons from tiered functional genomics.专性有机卤呼吸菌 Dehalobacter restrictus 的受限代谢:层次化功能基因组学的启示。
Philos Trans R Soc Lond B Biol Sci. 2013 Mar 11;368(1616):20120325. doi: 10.1098/rstb.2012.0325. Print 2013 Apr 19.
4
The transcriptional regulator CprK detects chlorination by combining direct and indirect readout mechanisms.转录调控因子 CprK 通过结合直接和间接读取机制来检测氯化作用。
Philos Trans R Soc Lond B Biol Sci. 2013 Mar 11;368(1616):20120323. doi: 10.1098/rstb.2012.0323. Print 2013 Apr 19.
5
Overview of organohalide-respiring bacteria and a proposal for a classification system for reductive dehalogenases.卤代烃呼吸细菌概述及还原脱卤酶分类系统建议
Philos Trans R Soc Lond B Biol Sci. 2013 Mar 11;368(1616):20120322. doi: 10.1098/rstb.2012.0322. Print 2013 Apr 19.
6
Organic cofactors in the metabolism of Dehalococcoides mccartyi strains.脱卤代菌属菌株代谢中的有机辅因子。
Philos Trans R Soc Lond B Biol Sci. 2013 Mar 11;368(1616):20120321. doi: 10.1098/rstb.2012.0321. Print 2013 Apr 19.
7
Guided cobalamin biosynthesis supports Dehalococcoides mccartyi reductive dechlorination activity.指导钴胺素生物合成支持 Dehalococcoides mccartyi 的还原脱氯活性。
Philos Trans R Soc Lond B Biol Sci. 2013 Mar 11;368(1616):20120320. doi: 10.1098/rstb.2012.0320. Print 2013 Apr 19.
8
The pentachlorophenol-dehalogenating Desulfitobacterium hafniense strain PCP-1.能够脱卤五氯酚的脱硫脱硫弧菌 PCP-1 菌株。
Philos Trans R Soc Lond B Biol Sci. 2013 Mar 11;368(1616):20120319. doi: 10.1098/rstb.2012.0319. Print 2013 Apr 19.
9
Identification of Dehalobacter reductive dehalogenases that catalyse dechlorination of chloroform, 1,1,1-trichloroethane and 1,1-dichloroethane.鉴定能够催化三氯甲烷、1,1,1-三氯乙烷和 1,1-二氯乙烷脱氯反应的脱硫弧菌还原脱卤酶。
Philos Trans R Soc Lond B Biol Sci. 2013 Mar 11;368(1616):20120318. doi: 10.1098/rstb.2012.0318. Print 2013 Apr 19.
10
Regulation of reductive dehalogenase gene transcription in Dehalococcoides mccartyi.调控地杆菌属中还原脱卤酶基因的转录。
Philos Trans R Soc Lond B Biol Sci. 2013 Mar 11;368(1616):20120317. doi: 10.1098/rstb.2012.0317. Print 2013 Apr 19.

有机卤呼吸:微生物呼吸氯化分子。

Organohalide respiration: microbes breathing chlorinated molecules.

机构信息

Manchester Institute of Biotechnology, University of Manchester, MIB 131 Princess Street, Manchester, UK.

出版信息

Philos Trans R Soc Lond B Biol Sci. 2013 Mar 11;368(1616):20120316. doi: 10.1098/rstb.2012.0316. Print 2013 Apr 19.

DOI:10.1098/rstb.2012.0316
PMID:23479746
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3638457/
Abstract

Bacterial respiration has taken advantage of almost every redox couple present in the environment. The reduction of organohalide compounds to release the reduced halide ion drives energy production in organohalide respiring bacteria. This process is centred around the reductive dehalogenases, an iron-sulfur and corrinoid containing family of enzymes. These enzymes, transcriptional regulators and the bacteria themselves have potential to contribute to future bioremediation solutions that address the pollution of the environment by halogenated organic compounds.

摘要

细菌呼吸利用了环境中几乎所有的氧化还原对。将有机卤化物化合物还原为释放还原卤化物离子的过程驱动有机卤化物呼吸细菌的能量产生。这个过程以还原脱卤酶为中心,还原脱卤酶是一种含铁硫和类咕啉的酶家族。这些酶、转录调节剂和细菌本身有可能为未来的生物修复解决方案做出贡献,这些解决方案可以解决环境中卤代有机化合物的污染问题。