Manchester Institute of Biotechnology, University of Manchester, MIB 131 Princess Street, Manchester, UK.
Philos Trans R Soc Lond B Biol Sci. 2013 Mar 11;368(1616):20120316. doi: 10.1098/rstb.2012.0316. Print 2013 Apr 19.
Bacterial respiration has taken advantage of almost every redox couple present in the environment. The reduction of organohalide compounds to release the reduced halide ion drives energy production in organohalide respiring bacteria. This process is centred around the reductive dehalogenases, an iron-sulfur and corrinoid containing family of enzymes. These enzymes, transcriptional regulators and the bacteria themselves have potential to contribute to future bioremediation solutions that address the pollution of the environment by halogenated organic compounds.
细菌呼吸利用了环境中几乎所有的氧化还原对。将有机卤化物化合物还原为释放还原卤化物离子的过程驱动有机卤化物呼吸细菌的能量产生。这个过程以还原脱卤酶为中心,还原脱卤酶是一种含铁硫和类咕啉的酶家族。这些酶、转录调节剂和细菌本身有可能为未来的生物修复解决方案做出贡献,这些解决方案可以解决环境中卤代有机化合物的污染问题。